PDB entry 4qi9
View 4qi9 on RCSB PDB site
Description: Crystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: structural genomics, Center for Structural Genomics of Infectious Diseases, CSGID, alpha beta fold, NIAID, National Institute of Allergy and Infectious Diseases, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on
2014-05-30, released
2014-07-02
The last revision prior to the SCOPe 2.04 freeze date was dated
2014-07-02, with a file datestamp of
2014-06-27.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.193
AEROSPACI score: 0.32
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: dihydrofolate reductase
Species: Yersinia pestis [TaxId:214092]
Gene: folA, y3688, YPO0486, YP_3693
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4qi9a_ - Chain 'B':
Compound: dihydrofolate reductase
Species: Yersinia pestis [TaxId:214092]
Gene: folA, y3688, YPO0486, YP_3693
Database cross-references and differences (RAF-indexed):
- Chain 'C':
Compound: dihydrofolate reductase
Species: Yersinia pestis [TaxId:214092]
Gene: folA, y3688, YPO0486, YP_3693
Database cross-references and differences (RAF-indexed):
- Heterogens: MTX, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4qi9A (A:)
miisliaalaadrvigmenampwhlpadlawfkrntlnkpvimgrktfesigrplpgrln
ivissqpgtdervtwaasieealafagnaeevmvmgggrvykqfldranrmylthidaev
ggdthfpdyepdewesvfsefhdadeanshsycfeilerrgenlyfq
Sequence, based on observed residues (ATOM records): (download)
>4qi9A (A:)
miisliaalaadrvilpadlawfkrntlnkpvimgrktfesigrplpgrlnivissqpgt
dervtwaasieealafagnaeevmvmgggrvykqfldranrmylthidaevggdthfpdy
epdewesvfsefhdadeanshsycfeilerrgenlyfq
- Chain 'B':
No sequence available.
- Chain 'C':
No sequence available.