PDB entry 4qbb

View 4qbb on RCSB PDB site
Description: Structure of the foot-and-mouth disease virus leader proteinase in complex with inhibitor (N~2~-[(3S)-4-({(2R)-1-[(4-CARBAMIMIDAMIDOBUTYL)AMINO]-4-METHYL-1-OXOPENTAN-2-YL}AMINO)-3-HYDROXY-4-OXOBUTANOYL]-L-ARGINYL-L-PROLINAMIDE)
Class: hydrolase/hydrolase inhibitor
Keywords: Papain-like cysteine proteinase, hydrolase-hydrolase inhibitor complex
Deposited on 2014-05-07, released 2014-11-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-11-05, with a file datestamp of 2014-10-31.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.171
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Leader protease
    Species: Foot-and-mouth disease virus [TaxId:73482]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03305 (0-End)
      • cloning artifact (97)
    Domains in SCOPe 2.08: d4qbba_
  • Chain 'B':
    Compound: Leader protease
    Species: Foot-and-mouth disease virus [TaxId:73482]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03305 (0-End)
      • cloning artifact (97)
    Domains in SCOPe 2.08: d4qbbb_
  • Chain 'C':
    Compound: Leader protease
    Species: Foot-and-mouth disease virus [TaxId:73482]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03305 (0-End)
      • cloning artifact (97)
    Domains in SCOPe 2.08: d4qbbc_
  • Heterogens: K, E69, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4qbbA (A:)
meltlyngekktfysrpnnhdncwlnailqlfryveepffdwvysspenltleaikqled
ltglelheggppalviwnikhllhtgigtasrpsevcvvdgtdmcladfhagiflkgqeh
avfacvtsngwyaiddedfypwtpdpsdvlvfvpydqeplngewkak

    Sequence, based on observed residues (ATOM records): (download) 
    >4qbbA (A:)
meltlyngekktfysrpnnhdncwlnailqlfryveepffdwvysspenltleaikqled
ltglelheggppalviwnikhllhtgigtasrpsevcvvdgtdmcladfhagiflkgqeh
avfacvtsngwyaiddedfypwtpdpsdvlvfvpydqep

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4qbbB (B:)
meltlyngekktfysrpnnhdncwlnailqlfryveepffdwvysspenltleaikqled
ltglelheggppalviwnikhllhtgigtasrpsevcvvdgtdmcladfhagiflkgqeh
avfacvtsngwyaiddedfypwtpdpsdvlvfvpydqeplngewkak

    Sequence, based on observed residues (ATOM records): (download) 
    >4qbbB (B:)
meltlyngekktfysrpnnhdncwlnailqlfryveepffdwvysspenltleaikqled
ltglelheggppalviwnikhllhtgigtasrpsevcvvdgtdmcladfhagiflkgqeh
avfacvtsngwyaiddedfypwtpdpsdvlvfvpyd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4qbbC (C:)
meltlyngekktfysrpnnhdncwlnailqlfryveepffdwvysspenltleaikqled
ltglelheggppalviwnikhllhtgigtasrpsevcvvdgtdmcladfhagiflkgqeh
avfacvtsngwyaiddedfypwtpdpsdvlvfvpydqeplngewkak

    Sequence, based on observed residues (ATOM records): (download) 
    >4qbbC (C:)
meltlyngekktfysrpnnhdncwlnailqlfryveepffdwvysspenltleaikqled
ltglelheggppalviwnikhllhtgigtasrpsevcvvdgtdmcladfhagiflkgqeh
avfacvtsngwyaiddedfypwtpdpsdvlvfvpydq