PDB entry 4q9s

View 4q9s on RCSB PDB site
Description: Crystal Structure of human Focal Adhesion Kinase (Fak) bound to Compound1 (3,5-DIHYDRO[1,2,4]TRIAZINO[3,4-C][1,4]BENZOXAZIN-2(1H)-ONE)
Class: Transferase/transferase inhibitor
Keywords: Kinase catalytic domain, Transferase-transferase inhibitor complex
Deposited on 2014-05-01, released 2014-07-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 2.07 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Focal adhesion kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PTK2, FAK, FAK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4q9sa_
  • Heterogens: 30G, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4q9sA (A:)
gamgsstrdyeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvr
ekflqealtmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslil
yayqlstalayleskrfvhrdiaarnvlvssndcvklgdfglsrymedstyykaskgklp
ikwmapesinfrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmpp
ncpptlyslmtkcwaydpsrrprftelkaqlstileeekaq

    Sequence, based on observed residues (ATOM records): (download) 
    >4q9sA (A:)
dyeiqrerielgrcigegqfgdvhqgiymsppalavaiktcknctsdsvrekflqealtm
rqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyayqlstala
yleskrfvhrdiaarnvlvssndcvklgdlpikwmapesinfrrftsasdvwmfgvcmwe
ilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydpsrrprftelka
qlstileeekaq