PDB entry 4q9j

View 4q9j on RCSB PDB site
Description: p-glycoprotein cocrystallised with qz-val
Deposited on 2014-05-01, released 2015-03-04
The last revision was dated 2015-03-18, with a file datestamp of 2015-03-13.
Experiment type: XRAY
Resolution: 3.6 Å
R-factor: N/A
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Multidrug resistance protein 1a
    Species: Mus musculus [TaxId:10090]
    Gene: Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21447 (Start-1275)
      • conflict (82)
      • conflict (86)
      • conflict (89)
      • expression tag (1276-1277)
  • Chain 'B':
    Compound: n-{[5-amino-1-(5-o-phosphono-beta-d-arabinofuranosyl)-1h-imidazol-4-yl]carbonyl}-l-aspartic acid
    Database cross-references and differences (RAF-indexed):
    • PDB 4Q9J (0-5)
  • Chain 'C':
    Compound: n-{[5-amino-1-(5-o-phosphono-beta-d-arabinofuranosyl)-1h-imidazol-4-yl]carbonyl}-l-aspartic acid
    Database cross-references and differences (RAF-indexed):
    • PDB 4Q9J (0-5)
  • Chain 'D':
    Compound: n-{[5-amino-1-(5-o-phosphono-beta-d-arabinofuranosyl)-1h-imidazol-4-yl]carbonyl}-l-aspartic acid
    Database cross-references and differences (RAF-indexed):
    • PDB 4Q9J (0-5)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4q9jA (A:)
meleedlkgradknfskmgkkskkekkekkpavsvltmfryagwldrlymlvgtlaaiih
gvalplmmlifgdmtdsfasvgqvskqstqmseadkramfakleeemttyayyytgigag
vlivayiqvsfwclaagrqihkirqkffhaimnqeigwfdvhdvgelntrltddvskine
gigdkigmffqamatffggfiigftrgwkltlvilaispvlglsagiwakilssftdkel
hayakagavaeevlaairtviafggqkkelerynnnleeakrlgikkaitanismgaafl
liyasyalafwygtslviskeysigqvltvffsvligafsvgqaspnieafanargaaye
vfkiidnkpsidsfsksghkpdniqgnlefknihfsypsrkevqilkglnlkvksgqtva
lvgnsgcgksttvqlmqrlydpldgmvsidgqdirtinvrylreiigvvsqepvlfatti
aenirygredvtmdeiekavkeanaydfimklphqfdtlvgergaqlsggqkqriaiara
lvrnpkillldeatsaldteseavvqaaldkaregrttiviahrlstvrnadviagfdgg
viveqgnhdelmrekgiyfklvmtqtagneielgneackskdeidnldmsskdsgsslir
rrstrksicgphdqdrklstkealdedvppasfwrilklnstewpyfvvgifcaiinggl
qpafsvifskvvgvftnggppetqrqnsnlfsllflilgiisfitfflqgftfgkageil
tkrlrymvfksmlrqdvswfddpknttgalttrlandaaqvkgatgsrlavifqnianlg
tgiiisliygwqltllllaivpiiaiagvvemkmlsgqalkdkkelegsgkiateaienf
rtvvsltreqkfetmyaqslqipyrnamkkahvfgitfsftqammyfsyaacfrfgaylv
tqqlmtfenvllvfsaivfgamavgqvssfapdyakatvsashiiriiektpeidsystq
glkpnmlegnvqfsgvvfnyptrpsipvlqglslevkkgqtlalvgssgcgkstvvqlle
rfydpmagsvfldgkeikqlnvqwlraqlgivsqepilfdcsiaeniaygdnsrvvsyee
ivraakeanihqfidslpdkyntrvgdkgtqlsggqkqriaiaralvrqphillldeats
aldtesekvvqealdkaregrtciviahrlstiqnadlivviqngkvkehgthqqllaqk
giyfsmvsvqagakrslehhhhhh

    Sequence, based on observed residues (ATOM records):
    >4q9jA (A:)
kpavsvltmfryagwldrlymlvgtlaaiihgvalplmmlifgdmtdsfasvgqvskqst
qmseadkramfakleeemttyayyytgigagvlivayiqvsfwclaagrqihkirqkffh
aimnqeigwfdvhdvgelntrltddvskinegigdkigmffqamatffggfiigftrgwk
ltlvilaispvlglsagiwakilssftdkelhayakagavaeevlaairtviafggqkke
lerynnnleeakrlgikkaitanismgaaflliyasyalafwygtslviskeysigqvlt
vffsvligafsvgqaspnieafanargaayevfkiidnkpsidsfsksghkpdniqgnle
fknihfsypsrkevqilkglnlkvksgqtvalvgnsgcgksttvqlmqrlydpldgmvsi
dgqdirtinvrylreiigvvsqepvlfattiaenirygredvtmdeiekavkeanaydfi
mklphqfdtlvgergaqlsggqkqriaiaralvrnpkillldeatsaldteseavvqaal
dkaregrttiviahrlstvrnadviagfdggviveqgnhdelmrekgiyfklvmtqtppa
sfwrilklnstewpyfvvgifcaiingglqpafsvifskvvgvftnggppetqrqnsnlf
sllflilgiisfitfflqgftfgkageiltkrlrymvfksmlrqdvswfddpknttgalt
trlandaaqvkgatgsrlavifqnianlgtgiiisliygwqltllllaivpiiaiagvve
mkmlsgqalkdkkelegsgkiateaienfrtvvsltreqkfetmyaqslqipyrnamkka
hvfgitfsftqammyfsyaacfrfgaylvtqqlmtfenvllvfsaivfgamavgqvssfa
pdyakatvsashiiriiektpeidsystqglkpnmlegnvqfsgvvfnyptrpsipvlqg
lslevkkgqtlalvgssgcgkstvvqllerfydpmagsvfldgkeikqlnvqwlraqlgi
vsqepilfdcsiaeniaygdnsrvvsyeeivraakeanihqfidslpdkyntrvgdkgtq
lsggqkqriaiaralvrqphillldeatsaldtesekvvqealdkaregrtciviahrls
tiqnadlivviqngkvkehgthqqllaqkgiyfsmvsvqagakrsle

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >4q9jB (B:)
xvxvxv

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >4q9jC (C:)
xvxvxv

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >4q9jD (D:)
xvxvxv