PDB entry 4q8q

View 4q8q on RCSB PDB site
Description: tRNA-Guanine Transglycosylase (TGT) Mutant V262C in Complex with 6-Amino-2-{[2-(morpholin-4-yl)ethyl]amino}-1H,7H,8H-imidazo[4,5-g]quinazolin-8-one
Class: Transferase/transferase inhibitor
Keywords: Transferase, preQ1, tRNA, Guanine Exchange Enzyme, Transferase-transferase inhibitor complex
Deposited on 2014-04-28, released 2015-05-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-05-20, with a file datestamp of 2015-05-15.
Experiment type: XRAY
Resolution: 1.72 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Queuine tRNA-ribosyltransferase
    Species: Zymomonas mobilis subsp. mobilis [TaxId:264203]
    Gene: tgt, ZMO0363
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28720
      • engineered mutation (263)
      • engineered mutation (313)
    Domains in SCOPe 2.08: d4q8qa_
  • Heterogens: ZN, CKR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4q8qA (A:)
gsmveataqetdrprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpet
vratgadiilgntyhlmlrpgaeriaklgglhsfmgwdrpiltdsggyqvmslssltkqs
eegvtfkshldgsrhmlspersieiqhllgsdivmafdectpypatpsraassmersmrw
akrsrdafdsrkeqaenaalfgiqqgsvfenlrqqsadalaeigfdgyavgglavgegqd
emfrvldfsvpmlpddkphylmgcgkpddivgavergidmfdcvlptrsgrngqaftwdg
pinirnarfsedlkpldsechcavcqkwsrayihhlirageilgamlmtehniafyqqlm
qkirdsisegrfsqfaqdfraryfarns

    Sequence, based on observed residues (ATOM records): (download) 
    >4q8qA (A:)
rprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpetvratgadiilgn
tyhlmlrpgaeriaklgglhsfmgwdrpiltdsggyqvmsltkqseegvtfkssrhmlsp
ersieiqhllgsdivmafdectpypatpsraassmersmrwakrsrdafdsrkeqaenaa
lfgiqqgsvfenlrqqsadalaeigfdgyavgglavgegqdemfrvldfsvpmlpddkph
ylmgcgkpddivgavergidmfdcvgqaftwdgpinirnarfsedlkpldsechcavcqk
wsrayihhlirageilgamlmtehniafyqqlmqkirdsisegrfsqfaqdfraryfa