PDB entry 4q5m

View 4q5m on RCSB PDB site
Description: D30N tethered HIV-1 protease dimer/saquinavir complex
Class: hydrolase/hydrolase inhibitor
Keywords: HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2014-04-17, released 2015-04-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-08-23, with a file datestamp of 2017-08-18.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protease
    Species: Human immunodeficiency virus type 1 [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04585 (104-202)
      • engineered mutation (29)
      • engineered mutation (94)
      • engineered mutation (133)
      • engineered mutation (198)
    Domains in SCOPe 2.08: d4q5ma1, d4q5ma2
  • Heterogens: ROC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4q5mA (A:)
pqvtlwqrplvtikiggqlkealldtgadntvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigmtlnfggssgpqvtlwqrplvtikig
gqlkealldtgadntvleemslpgrwkpkmiggiggfikvrqydqilieicghkaigtvl
vgptpvniigrnlltqigatlnf

    Sequence, based on observed residues (ATOM records): (download) 
    >4q5mA (A:)
pqvtlwqrplvtikiggqlkealldtgadntvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigmtlnfpqvtlwqrplvtikiggqlke
alldtgadntvleemslpgrwkpkmiggiggfikvrqydqilieicghkaigtvlvgptp
vniigrnlltqigatlnf