PDB entry 4q5e

View 4q5e on RCSB PDB site
Description: Shigella Effector Kinase OspG bound to E2-Ub UbcH7-Ub Conjugate
Class: unknown function, protein binding
Keywords: protein-protein complex, Structural Genomics, Montreal-Kingston Bacterial Structural Genomics Initiative, BSGI, kinase fold, inhibition of NF-kB pathway, UNKNOWN FUNCTION, PROTEIN BINDING
Deposited on 2014-04-16, released 2014-07-02
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-07-09, with a file datestamp of 2014-07-03.
Experiment type: XRAY
Resolution: 1.87 Å
R-factor: 0.187
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein kinase ospg
    Species: Shigella sonnei Ss046 [TaxId:300269]
    Gene: ospG, SSON_P170
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Polyubiquitin
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: SCD2, UBE2L3, UBI4, YLL039C
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG63 (0-75)
      • engineered mutation (47)
      • engineered mutation (75)
    Domains in SCOPe 2.05: d4q5eb_
  • Chain 'C':
    Compound: Ubiquitin-conjugating enzyme E2 L3
    Species: Homo sapiens [TaxId:9606]
    Gene: UBCE7, UBCH7, UBE2L3, UBI4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68036 (2-155)
      • expression tag (1)
      • engineered mutation (18)
      • engineered mutation (138)
    Domains in SCOPe 2.05: d4q5ec_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4q5eB (B:)
    mqifvktltgktitlevessdtidnvkskiqdkegippdqqrlifagrqledgrtlsdyn
    iqkestlhlvlrlrgc
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4q5eC (C:)
    ghmaasrrlmkeleeirksgmknfrniqvdeanlltwqglivpdnppydkgafrieinfp
    aeypfkppkitfktkiyhpnidekgqvclpvisaenwkpatktdqviqslialvndpqpe
    hplradlaeeyskdrkkfsknaeeftkkygekrpvd
    

    Sequence, based on observed residues (ATOM records): (download)
    >4q5eC (C:)
    hmaasrrlmkeleeirksgmknfrniqvdeanlltwqglivpdnppydkgafrieinfpa
    eypfkppkitfktkiyhpnidekgqvclpvisaenwkpatktdqviqslialvndpqpeh
    plradlaeeyskdrkkfsknaeeftkkygekrpvd