PDB entry 4q4c

View 4q4c on RCSB PDB site
Description: Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP and synthetic 1,5-(PP)2-IP4 (1,5-IP8)
Deposited on 2014-04-14, released 2014-08-06
The last revision was dated 2014-09-10, with a file datestamp of 2014-09-05.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.163
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: PPIP5K2, HISPPD1, KIAA0433, VIP2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ADP, I8P, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4q4cA (A:)
gsfterqivvgicsmakkskskpmkeilerislfkyitvvvfeeevilnepvenwplcdc
lisfhskgfpldkavayaklrnpfvindlnmqyliqdrrevysilqaegillpryailnr
dpnnpkecnliegedhvevngevfqkpfvekpvsaedhnvyiyyptsagggsqrlfrkig
srssvyspesnvrktgsyiyeefmptdgtdvkvytvgpdyahaearkspaldgkverdse
gkevrypvilnarekliawkvclafkqtvcgfdllrangqsyvcdvngfsfvknsmkyyd
dcakilgnivmrelapqfhipwsipleaed

    Sequence, based on observed residues (ATOM records):
    >4q4cA (A:)
rqivvgicsmakkskskpmkeilerislfkyitvvvfeeevilnepvenwplcdclisfh
skgfpldkavayaklrnpfvindlnmqyliqdrrevysilqaegillpryailnrdpnnp
kecnliegedhvevngevfqkpfvekpvsaedhnvyiyyptsagggsqrlfrkigsrssv
yspesnvrktgsyiyeefmptdgtdvkvytvgpdyahaearkspaldgkverdsegkevr
ypvilnarekliawkvclafkqtvcgfdllrangqsyvcdvngfsfvknsmkyyddcaki
lgnivmrelapqfhipwsipleaed