PDB entry 4q3w

View 4q3w on RCSB PDB site
Description: Crystal structure of C. violaceum phenylalanine hydroxylase D139E mutation
Class: oxidoreductase
Keywords: Mutation, hydroxylase, phenylalanine hydroxylase, kinetics, metals, Chromobacterium, phenylketonurias, biopterin, Mixed alpha helix-beta sheet, OXIDOREDUCTASE
Deposited on 2014-04-12, released 2015-02-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-20, with a file datestamp of 2019-11-15.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phenylalanine-4-hydroxylase
    Species: Chromobacterium violaceum [TaxId:243365]
    Gene: phhA, CV_3180
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30967
      • conflict (63)
      • conflict (84)
      • engineered mutation (138)
      • conflict (275)
    Domains in SCOPe 2.08: d4q3wa_
  • Heterogens: CO, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4q3wA (A:)
mndradfvvpdittrknvglshdandftlpqpldrysaedhatwatlyqrqckllpgrac
defleglerlevdadrvpdfnklneklmaatgwkivavpglipddvffehlanrrfpvtw
wlrephqldylqepdvfhelfghvpllinpvfadyleaygkggvkakalgalpmlarlyw
ytvefglintpagmriygagilssksesiycldsaspnrvgfdlmrimntryridtfqkt
yfvidsfkqlfdatapdfaplylqladaqpwgagdiapddlvlnagdrqgwadtedv

    Sequence, based on observed residues (ATOM records): (download) 
    >4q3wA (A:)
fvvpdittrknvglshdandftlpqpldrysaedhatwatlyqrqckllpgracdefleg
lerlevdadrvpdfnklneklmaatgwkivavpglipddvffehlanrrfpvtwwlreph
qldylqepdvfhelfghvpllinpvfadyleaygkggvkakalgalpmlarlywytvefg
lintpagmriygagilssksesiycldsaspnrvgfdlmrimntryridtfqktyfvids
fkqlfdatapdfaplylqladaqpwgagdiapddlvl