PDB entry 4q3v

View 4q3v on RCSB PDB site
Description: Crystal structure of Schistosoma mansoni arginase in complex with inhibitor BEC
Class: hydrolase/hydrolase inhibitor
Keywords: arginase-deacetylase fold, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2014-04-12, released 2014-07-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-08-06, with a file datestamp of 2014-08-01.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.17
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: arginase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: Smp_059980
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4q3va_
  • Chain 'B':
    Compound: arginase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: Smp_059980
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4q3vb_
  • Chain 'C':
    Compound: arginase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: Smp_059980
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4q3vc_
  • Chain 'D':
    Compound: arginase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: Smp_059980
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4q3vd_
  • Heterogens: MN, GOL, S2C, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4q3vA (A:)
mgsshhhhhhssglvprgshmmlksvatpyypiqdekpkllytsanflgiptnrgqpkig
tyqgpelirksnffqlvaedgiqltdcgdiipvelneaedpqrfgmkwsrsfslttlria
erveelmkqsnkhtvelsgskstplvivggdhsmatgtilghaeakpdlcvlwidahgdi
ntplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasniayiglrdldahethd
irkhgiayftmldvdrmgieavikeallavnprlekaihlsfdidaldplvapstgtavp
ggltlreglriceevsatgklsvvelaelnpllgsqedvlktqssavhilraclghcrsg
hlpfkvrnltdqgimsraahmqtkq

    Sequence, based on observed residues (ATOM records): (download) 
    >4q3vA (A:)
pkllytsanflgiptnrgqpkigtyqgpelirksnffqlvaedgiqltdcgdiipvelne
aedpqrfgmkwsrsfslttlriaerveelmkqsnkstplvivggdhsmatgtilghaeak
pdlcvlwidahgdintplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasnia
yiglrdldahethdirkhgiayftmldvdrmgieavikeallavnprlekaihlsfdida
ldplvapstgtavpggltlreglriceevsatgklsvvelaelnpllgsqedvlktqssa
vhilraclghcrsghlpfkvrnltdqgimsraahmqt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4q3vB (B:)
mgsshhhhhhssglvprgshmmlksvatpyypiqdekpkllytsanflgiptnrgqpkig
tyqgpelirksnffqlvaedgiqltdcgdiipvelneaedpqrfgmkwsrsfslttlria
erveelmkqsnkhtvelsgskstplvivggdhsmatgtilghaeakpdlcvlwidahgdi
ntplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasniayiglrdldahethd
irkhgiayftmldvdrmgieavikeallavnprlekaihlsfdidaldplvapstgtavp
ggltlreglriceevsatgklsvvelaelnpllgsqedvlktqssavhilraclghcrsg
hlpfkvrnltdqgimsraahmqtkq

    Sequence, based on observed residues (ATOM records): (download) 
    >4q3vB (B:)
pkllytsanflgiptnrgqpkigtyqgpelirksnffqlvaedgiqltdcgdiipvelne
aedpqrfgmkwsrsfslttlriaerveelmkqsnkkstplvivggdhsmatgtilghaea
kpdlcvlwidahgdintplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasni
ayiglrdldahethdirkhgiayftmldvdrmgieavikeallavnprlekaihlsfdid
aldplvapstgtavpggltlreglriceevsatgklsvvelaelnpllgsqedvlktqss
avhilraclghcrsghlpfkvrnltdqgimsraahmqt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4q3vC (C:)
mgsshhhhhhssglvprgshmmlksvatpyypiqdekpkllytsanflgiptnrgqpkig
tyqgpelirksnffqlvaedgiqltdcgdiipvelneaedpqrfgmkwsrsfslttlria
erveelmkqsnkhtvelsgskstplvivggdhsmatgtilghaeakpdlcvlwidahgdi
ntplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasniayiglrdldahethd
irkhgiayftmldvdrmgieavikeallavnprlekaihlsfdidaldplvapstgtavp
ggltlreglriceevsatgklsvvelaelnpllgsqedvlktqssavhilraclghcrsg
hlpfkvrnltdqgimsraahmqtkq

    Sequence, based on observed residues (ATOM records): (download) 
    >4q3vC (C:)
kpkllytsanflgiptnrgqpkigtyqgpelirksnffqlvaedgiqltdcgdiipveln
eaedpqrfgmkwsrsfslttlriaerveelmkqsnkkstplvivggdhsmatgtilghae
akpdlcvlwidahgdintplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasn
iayiglrdldahethdirkhgiayftmldvdrmgieavikeallavnprlekaihlsfdi
daldplvapstgtavpggltlreglriceevsatgklsvvelaelnpllgsqedvlktqs
savhilraclghcrsghlpfkvrnltdqgimsraahmqt

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4q3vD (D:)
mgsshhhhhhssglvprgshmmlksvatpyypiqdekpkllytsanflgiptnrgqpkig
tyqgpelirksnffqlvaedgiqltdcgdiipvelneaedpqrfgmkwsrsfslttlria
erveelmkqsnkhtvelsgskstplvivggdhsmatgtilghaeakpdlcvlwidahgdi
ntplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasniayiglrdldahethd
irkhgiayftmldvdrmgieavikeallavnprlekaihlsfdidaldplvapstgtavp
ggltlreglriceevsatgklsvvelaelnpllgsqedvlktqssavhilraclghcrsg
hlpfkvrnltdqgimsraahmqtkq

    Sequence, based on observed residues (ATOM records): (download) 
    >4q3vD (D:)
llytsanflgiptnrgqpkigtyqgpelirksnffqlvaedgiqltdcgdiipvelneae
dpqrfgmkwsrsfslttlriaerveelmkstplvivggdhsmatgtilghaeakpdlcvl
widahgdintplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasniayiglrd
ldahethdirkhgiayftmldvdrmgieavikeallavnprlekaihlsfdidaldplva
pstgtavpggltlreglriceevsatgklsvvelaelnpllgsqedvlktqssavhilra
clghcrsghlpfkvrnltdqgimsraahm