PDB entry 4q3q

View 4q3q on RCSB PDB site
Description: Crystal structure of Schistosoma mansoni arginase in complex with inhibitor ABH
Class: hydrolase/hydrolase inhibitor
Keywords: arginase-deacetylase fold, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2014-04-12, released 2014-07-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-08-06, with a file datestamp of 2014-08-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.17
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: arginase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: Smp_059980
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4q3qa_
  • Chain 'B':
    Compound: arginase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: Smp_059980
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4q3qb_
  • Chain 'C':
    Compound: arginase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: Smp_059980
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4q3qc_
  • Chain 'D':
    Compound: arginase
    Species: Schistosoma mansoni [TaxId:6183]
    Gene: Smp_059980
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4q3qd_
  • Heterogens: MN, GOL, ABH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4q3qA (A:)
mgsshhhhhhssglvprgshmmlksvatpyypiqdekpkllytsanflgiptnrgqpkig
tyqgpelirksnffqlvaedgiqltdcgdiipvelneaedpqrfgmkwsrsfslttlria
erveelmkqsnkhtvelsgskstplvivggdhsmatgtilghaeakpdlcvlwidahgdi
ntplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasniayiglrdldahethd
irkhgiayftmldvdrmgieavikeallavnprlekaihlsfdidaldplvapstgtavp
ggltlreglriceevsatgklsvvelaelnpllgsqedvlktqssavhilraclghcrsg
hlpfkvrnltdqgimsraahmqtkq

    Sequence, based on observed residues (ATOM records): (download) 
    >4q3qA (A:)
kllytsanflgiptnrgqpkigtyqgpelirksnffqlvaedgiqltdcgdiipvelnea
edpqrfgmkwsrsfslttlriaerveelmkqsnkstplvivggdhsmatgtilghaeakp
dlcvlwidahgdintplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasniay
iglrdldahethdirkhgiayftmldvdrmgieavikeallavnprlekaihlsfdidal
dplvapstgtavpggltlreglriceevsatgklsvvelaelnpllgsqedvlktqssav
hilraclghcrsghlpfkvrnltdqgimsraahmq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4q3qB (B:)
mgsshhhhhhssglvprgshmmlksvatpyypiqdekpkllytsanflgiptnrgqpkig
tyqgpelirksnffqlvaedgiqltdcgdiipvelneaedpqrfgmkwsrsfslttlria
erveelmkqsnkhtvelsgskstplvivggdhsmatgtilghaeakpdlcvlwidahgdi
ntplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasniayiglrdldahethd
irkhgiayftmldvdrmgieavikeallavnprlekaihlsfdidaldplvapstgtavp
ggltlreglriceevsatgklsvvelaelnpllgsqedvlktqssavhilraclghcrsg
hlpfkvrnltdqgimsraahmqtkq

    Sequence, based on observed residues (ATOM records): (download) 
    >4q3qB (B:)
kllytsanflgiptnrgqpkigtyqgpelirksnffqlvaedgiqltdcgdiipvelnea
edpqrfgmkwsrsfslttlriaerveelmkqsnkstplvivggdhsmatgtilghaeakp
dlcvlwidahgdintplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasniay
iglrdldahethdirkhgiayftmldvdrmgieavikeallavnprlekaihlsfdidal
dplvapstgtavpggltlreglriceevsatgklsvvelaelnpllgsqedvlktqssav
hilraclghcrsghlpfkvrnltdqgimsraahmq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4q3qC (C:)
mgsshhhhhhssglvprgshmmlksvatpyypiqdekpkllytsanflgiptnrgqpkig
tyqgpelirksnffqlvaedgiqltdcgdiipvelneaedpqrfgmkwsrsfslttlria
erveelmkqsnkhtvelsgskstplvivggdhsmatgtilghaeakpdlcvlwidahgdi
ntplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasniayiglrdldahethd
irkhgiayftmldvdrmgieavikeallavnprlekaihlsfdidaldplvapstgtavp
ggltlreglriceevsatgklsvvelaelnpllgsqedvlktqssavhilraclghcrsg
hlpfkvrnltdqgimsraahmqtkq

    Sequence, based on observed residues (ATOM records): (download) 
    >4q3qC (C:)
kllytsanflgiptnrgqpkigtyqgpelirksnffqlvaedgiqltdcgdiipvelnea
edpqrfgmkwsrsfslttlriaerveelmkqsnstplvivggdhsmatgtilghaeakpd
lcvlwidahgdintplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasniayi
glrdldahethdirkhgiayftmldvdrmgieavikeallavnprlekaihlsfdidald
plvapstgtavpggltlreglriceevsatgklsvvelaelnpllgsqedvlktqssavh
ilraclghcrsghlpfkvrnltdqgimsraahmqt

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4q3qD (D:)
mgsshhhhhhssglvprgshmmlksvatpyypiqdekpkllytsanflgiptnrgqpkig
tyqgpelirksnffqlvaedgiqltdcgdiipvelneaedpqrfgmkwsrsfslttlria
erveelmkqsnkhtvelsgskstplvivggdhsmatgtilghaeakpdlcvlwidahgdi
ntplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasniayiglrdldahethd
irkhgiayftmldvdrmgieavikeallavnprlekaihlsfdidaldplvapstgtavp
ggltlreglriceevsatgklsvvelaelnpllgsqedvlktqssavhilraclghcrsg
hlpfkvrnltdqgimsraahmqtkq

    Sequence, based on observed residues (ATOM records): (download) 
    >4q3qD (D:)
llytsanflgiptnrgqpkigtyqgpelirksnffqlvaedgiqltdcgdiipvelneae
dpqrfgmkwsrsfslttlriaerveelmkqstplvivggdhsmatgtilghaeakpdlcv
lwidahgdintplnsasgnmhgmplsflvkelqdqipwlddfegikpclnasniayiglr
dldahethdirkhgiayftmldvdrmgieavikeallavnprlekaihlsfdidaldplv
apstgtavpggltlreglriceevsatgklsvvelaelnpllgsqedvlktqssavhilr
aclghcrsghlpfkvrnltdqgimsraahm