PDB entry 4q32

View 4q32 on RCSB PDB site
Description: Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and C91
Class: oxidoreductase
Keywords: structural genomics, NIAID, National Institute of Allergy and Infectious Diseases, Center for Structural Genomics of Infectious Diseases, CSGID, TIM barrel, dehydrogenase, OXIDOREDUCTASE
Deposited on 2014-04-10, released 2014-07-09
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-07-09, with a file datestamp of 2014-07-03.
Experiment type: XRAY
Resolution: 2.79 Å
R-factor: 0.176
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Clostridium perfringens [TaxId:195103]
    Gene: CPF_2558, guaB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0TN42 (Start-90)
    • Uniprot Q0TN42 (94-End)
      • linker (91-93)
    Domains in SCOPe 2.06: d4q32a_
  • Chain 'B':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Clostridium perfringens [TaxId:195103]
    Gene: CPF_2558, guaB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0TN42 (Start-90)
    • Uniprot Q0TN42 (94-End)
      • linker (91-93)
    Domains in SCOPe 2.06: d4q32b_
  • Chain 'C':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Clostridium perfringens [TaxId:195103]
    Gene: CPF_2558, guaB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0TN42 (Start-90)
    • Uniprot Q0TN42 (94-End)
      • linker (91-93)
    Domains in SCOPe 2.06: d4q32c_
  • Chain 'D':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Clostridium perfringens [TaxId:195103]
    Gene: CPF_2558, guaB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q0TN42 (Start-90)
    • Uniprot Q0TN42 (94-End)
      • linker (91-93)
    Domains in SCOPe 2.06: d4q32d_
  • Heterogens: IMP, C91, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4q32A (A:)
snamarilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskm
aiamareggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvd
vivldtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgs
icttrivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsi
fagceeapgaieiyqgrsykvyrgmgslgamakgssdryfqngtkkfvpegvegriaykg
hladtiyqliggiksgmgylgaptlenlyenanfvvqtsagfreshphdinitkeapnys
vnq

    Sequence, based on observed residues (ATOM records): (download) 
    >4q32A (A:)
ktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskmaiamareg
gigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvdvivldtah
ghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgsicttriva
gvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsifagceeap
gaieiyqgrsykvyrgmgslgamavpegvegriaykghladtiyqliggiksgmgylgap
tlenlyenanfvvqtsagfreshphdinitkeapnys

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4q32B (B:)
snamarilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskm
aiamareggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvd
vivldtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgs
icttrivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsi
fagceeapgaieiyqgrsykvyrgmgslgamakgssdryfqngtkkfvpegvegriaykg
hladtiyqliggiksgmgylgaptlenlyenanfvvqtsagfreshphdinitkeapnys
vnq

    Sequence, based on observed residues (ATOM records): (download) 
    >4q32B (B:)
ilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskmaiamar
eggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvdvivldt
ahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgsicttri
vagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsifagcee
apgaieiyqgrsykvyrgmgslgamakgvpegvegriaykghladtiyqliggiksgmgy
lgaptlenlyenanfvvqtsagfreshphdinitkeapnys

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4q32C (C:)
snamarilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskm
aiamareggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvd
vivldtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgs
icttrivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsi
fagceeapgaieiyqgrsykvyrgmgslgamakgssdryfqngtkkfvpegvegriaykg
hladtiyqliggiksgmgylgaptlenlyenanfvvqtsagfreshphdinitkeapnys
vnq

    Sequence, based on observed residues (ATOM records): (download) 
    >4q32C (C:)
ilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskmaiamar
eggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvdvivldt
ahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgsicttri
vagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsifagcee
apgaieiyqgrsykvyrgmgslgamakfvpegvegriaykghladtiyqliggiksgmgy
lgaptlenlyenanfvvqtsagfreshphdinitkeapnys

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4q32D (D:)
snamarilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskm
aiamareggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvd
vivldtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgs
icttrivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsi
fagceeapgaieiyqgrsykvyrgmgslgamakgssdryfqngtkkfvpegvegriaykg
hladtiyqliggiksgmgylgaptlenlyenanfvvqtsagfreshphdinitkeapnys
vnq

    Sequence, based on observed residues (ATOM records): (download) 
    >4q32D (D:)
ilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskmaiamar
eggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvdvivldt
ahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgsicttri
vagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsifagcee
apgaieiyqgrsykvyrgmgslgamavpegvegriaykghladtiyqliggiksgmgylg
aptlenlyenanfvvqtsagfreshphdinitkeapnys