PDB entry 4q2z

View 4q2z on RCSB PDB site
Description: Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE356, from a non-human primate
Class: immune system
Keywords: Fab fragment, HIV viral envelope glycoprotein neutralization, IMMUNE SYSTEM
Deposited on 2014-04-10, released 2014-09-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-09-17, with a file datestamp of 2014-09-12.
Experiment type: XRAY
Resolution: 1.93 Å
R-factor: 0.234
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heavy chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody
    Species: MACACA MULATTA [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 4Q2Z (0-End)
    Domains in SCOPe 2.08: d4q2za_
  • Chain 'B':
    Compound: Light chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody
    Species: MACACA MULATTA [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 4Q2Z (0-211)
    Domains in SCOPe 2.08: d4q2zb1, d4q2zb2
  • Chain 'H':
    Compound: Heavy chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody
    Species: MACACA MULATTA [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 4Q2Z (0-End)
    Domains in SCOPe 2.08: d4q2zh_
  • Chain 'L':
    Compound: Light chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody
    Species: MACACA MULATTA [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 4Q2Z (0-211)
    Domains in SCOPe 2.08: d4q2zl1, d4q2zl2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4q2zA (A:)
evqlvqsgaevkkpgssvkvsckasgytftdyymhwvrqapgqglewmgqinpktggtny
aqkfqgrvtmtrdtststaymelsslrsedtaiyycarggqrllllrnyyfyywgqgvlv
tvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpav
lqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkshhhhhhp

    Sequence, based on observed residues (ATOM records): (download) 
    >4q2zA (A:)
evqlvqsgaevkkpgssvkvsckasgytftdyymhwvrqapgqglewmgqinpktggtny
aqkfqgrvtmtrdtststaymelsslrsedtaiyycarggqrllllrnyyfyywgqgvlv
tvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpav
lqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvep

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4q2zB (B:)
qsvltqppsvsgapgqkvtisctgsssniggydvhwyqqlpgmapklliydnnerpsgis
drfsgsksatsaslaitglqtedeadyycqsydsslnawvfgggtrltvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvap

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4q2zH (H:)
evqlvqsgaevkkpgssvkvsckasgytftdyymhwvrqapgqglewmgqinpktggtny
aqkfqgrvtmtrdtststaymelsslrsedtaiyycarggqrllllrnyyfyywgqgvlv
tvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpav
lqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkshhhhhhp

    Sequence, based on observed residues (ATOM records): (download) 
    >4q2zH (H:)
evqlvqsgaevkkpgssvkvsckasgytftdyymhwvrqapgqglewmgqinpktggtny
aqkfqgrvtmtrdtststaymelsslrsedtaiyycarggqrllllrnyyfyywgqgvlv
tvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpav
lqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvep

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4q2zL (L:)
qsvltqppsvsgapgqkvtisctgsssniggydvhwyqqlpgmapklliydnnerpsgis
drfsgsksatsaslaitglqtedeadyycqsydsslnawvfgggtrltvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvap