PDB entry 4q2u

View 4q2u on RCSB PDB site
Description: Crystal structure of the E. coli DinJ-YafQ toxin-antitoxin complex
Class: toxin/toxin repressor
Keywords: Bacterial Toxin-Antitoxin complex, Translation control, RHH motif, Ribonuclease, DNA binding, Ribosome binding, TOXIN-TOXIN REPRESSOR complex
Deposited on 2014-04-09, released 2014-06-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-08-06, with a file datestamp of 2014-08-01.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.178
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Antitoxin DinJ
  Species: Escherichia coli [TaxId:83333]
  Gene: dinJ, b0226, JW0216
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47150 (Start-85)
• Chain 'B':
  Compound: mRNA interferase YafQ
  Species: Escherichia coli [TaxId:83333]
  Gene: yafQ, b0225, JW0215
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47149 (Start-101)
  Domains in SCOPe 2.08: d4q2ub_
• Chain 'C':
  Compound: Antitoxin DinJ
  Species: Escherichia coli [TaxId:83333]
  Gene: dinJ, b0226, JW0216
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47150 (Start-85)
• Chain 'D':
  Compound: mRNA interferase YafQ
  Species: Escherichia coli [TaxId:83333]
  Gene: yafQ, b0225, JW0215
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47149 (Start-101)
  Domains in SCOPe 2.08: d4q2ud_
• Chain 'E':
  Compound: Antitoxin DinJ
  Species: Escherichia coli [TaxId:83333]
  Gene: dinJ, b0226, JW0216
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47150 (Start-85)
• Chain 'F':
  Compound: mRNA interferase YafQ
  Species: Escherichia coli [TaxId:83333]
  Gene: yafQ, b0225, JW0215
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47149 (Start-101)
  Domains in SCOPe 2.08: d4q2uf_
• Chain 'G':
  Compound: Antitoxin DinJ
  Species: Escherichia coli [TaxId:83333]
  Gene: dinJ, b0226, JW0216
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47150 (Start-85)
• Chain 'H':
  Compound: mRNA interferase YafQ
  Species: Escherichia coli [TaxId:83333]
  Gene: yafQ, b0225, JW0215
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47149 (Start-101)
  Domains in SCOPe 2.08: d4q2uh_
• Chain 'I':
  Compound: Antitoxin DinJ
  Species: Escherichia coli [TaxId:83333]
  Gene: dinJ, b0226, JW0216
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47150 (Start-85)
• Chain 'J':
  Compound: mRNA interferase YafQ
  Species: Escherichia coli [TaxId:83333]
  Gene: yafQ, b0225, JW0215
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47149 (Start-101)
  Domains in SCOPe 2.08: d4q2uj_
• Chain 'K':
  Compound: Antitoxin DinJ
  Species: Escherichia coli [TaxId:83333]
  Gene: dinJ, b0226, JW0216
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47150 (Start-85)
• Chain 'L':
  Compound: mRNA interferase YafQ
  Species: Escherichia coli [TaxId:83333]
  Gene: yafQ, b0225, JW0215
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47149 (11-101)
  Domains in SCOPe 2.08: d4q2ul_
• Chain 'M':
  Compound: Antitoxin DinJ
  Species: Escherichia coli [TaxId:83333]
  Gene: dinJ, b0226, JW0216
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47150 (Start-85)
• Chain 'N':
  Compound: mRNA interferase YafQ
  Species: Escherichia coli [TaxId:83333]
  Gene: yafQ, b0225, JW0215
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47149 (Start-101)
  Domains in SCOPe 2.08: d4q2un_
• Chain 'O':
  Compound: Antitoxin DinJ
  Species: Escherichia coli [TaxId:83333]
  Gene: dinJ, b0226, JW0216
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47150 (Start-85)
• Chain 'P':
  Compound: mRNA interferase YafQ
  Species: Escherichia coli [TaxId:83333]
  Gene: yafQ, b0225, JW0215
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q47149 (Start-101)
  Domains in SCOPe 2.08: d4q2up_
• Heterogens: SO4, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  Sequence, based on SEQRES records: (download)
  

  >4q2uB (B:)
  mhhhhhhdlgtiqrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdh
  plqgswkgyrdahvepdwiliykltdkllrfertgthaalfg
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4q2uB (B:)
  qrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdhplqgswkgyrda
  hvepdwiliykltdkllrfertgthaalfg
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  Sequence, based on SEQRES records: (download)
  

  >4q2uD (D:)
  mhhhhhhdlgtiqrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdh
  plqgswkgyrdahvepdwiliykltdkllrfertgthaalfg
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4q2uD (D:)
  qrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdhplqgswkgyrda
  hvepdwiliykltdkllrfertgthaalfg
  

  
  
• Chain 'E':
  No sequence available.
  
  
• Chain 'F':
  Sequence, based on SEQRES records: (download)
  

  >4q2uF (F:)
  mhhhhhhdlgtiqrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdh
  plqgswkgyrdahvepdwiliykltdkllrfertgthaalfg
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4q2uF (F:)
  qrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdhplqgswkgyrda
  hvepdwiliykltdkllrfertgthaalfg
  

  
  
• Chain 'G':
  No sequence available.
  
  
• Chain 'H':
  Sequence, based on SEQRES records: (download)
  

  >4q2uH (H:)
  mhhhhhhdlgtiqrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdh
  plqgswkgyrdahvepdwiliykltdkllrfertgthaalfg
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4q2uH (H:)
  qrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdhplqgswkgyrda
  hvepdwiliykltdkllrfertgthaalfg
  

  
  
• Chain 'I':
  No sequence available.
  
  
• Chain 'J':
  Sequence, based on SEQRES records: (download)
  

  >4q2uJ (J:)
  mhhhhhhdlgtiqrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdh
  plqgswkgyrdahvepdwiliykltdkllrfertgthaalfg
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4q2uJ (J:)
  qrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdhplqgswkgyrda
  hvepdwiliykltdkllrfertgthaalfg
  

  
  
• Chain 'K':
  No sequence available.
  
  
• Chain 'L':
  Sequence, based on SEQRES records: (download)
  

  >4q2uL (L:)
  mhhhhhhdlgtiqrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdh
  plqgswkgyrdahvepdwiliykltdkllrfertgthaalfg
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4q2uL (L:)
  iqrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdhplqgswkgyrd
  ahvepdwiliykltdkllrfertgthaalfg
  

  
  
• Chain 'M':
  No sequence available.
  
  
• Chain 'N':
  Sequence, based on SEQRES records: (download)
  

  >4q2uN (N:)
  mhhhhhhdlgtiqrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdh
  plqgswkgyrdahvepdwiliykltdkllrfertgthaalfg
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4q2uN (N:)
  qrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdhplqgswkgyrda
  hvepdwiliykltdkllrfertgthaalfg
  

  
  
• Chain 'O':
  No sequence available.
  
  
• Chain 'P':
  Sequence, based on SEQRES records: (download)
  

  >4q2uP (P:)
  mhhhhhhdlgtiqrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdh
  plqgswkgyrdahvepdwiliykltdkllrfertgthaalfg
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4q2uP (P:)
  qrdieysgqyskdvklaqkrhkdmnklkylmtllinntlplpavykdhplqgswkgyrda
  hvepdwiliykltdkllrfertgthaalfg