PDB entry 4q2t

View 4q2t on RCSB PDB site
Description: crystal structure of arginyl-trna synthetase complexed with l-arginine
Deposited on 2014-04-09, released 2014-07-23
The last revision was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Arginine--tRNA ligase, cytoplasmic
    Species: Homo sapiens [TaxId:9606]
    Gene: RARS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54136 (19-606)
      • expression tag (17-18)
      • engineered mutation (456)
  • Chain 'B':
    Compound: Arginine--tRNA ligase, cytoplasmic
    Species: Homo sapiens [TaxId:9606]
    Gene: RARS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54136 (19-606)
      • expression tag (17-18)
      • engineered mutation (456)
  • Heterogens: ARG, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4q2tA (A:)
    hhhhhhssglvprgshmasminiisrlqevfghaikaaypdlenppllvtpsqqakfgdy
    qcnsamgisqmlktkeqkvnpreiaenitkhlpdneciekveiagpgfinvhlrkdfvse
    qltsllvngvqlpalgenkkvivdfsspniakemhvghlrstiigesisrlfefagydvl
    rlnhvgdwgtqfgmliahlqdkfpdyltvsppigdlqvfykeskkrfdteeefkkrayqc
    vvllqgknpditkawklicdvsrqelnkiydaldvsliergesfyqdrmndivkefedrg
    fvqvddgrkivfvpgcsipltivksdggytydtsdlaaikqrlfeekadmiiyvvdngqs
    vhfqtifaaaqmigwydpkvtrvfhagfgvvlgedkkkfktrsgetvrlmdllgeglkrs
    mdklkekerdkvltaeelnaaqtsvaygcikyadlsrnrlndyifsfdkmlddrgntaay
    llyaftrirsiarlanideemlqkaaretkilldhekewklgrcilrfpeilqkilddlf
    lhtlcdyiyelataftefydscycvekdrqtgkilkvnmwrmllceavaavmakgfdilg
    ikpvqrm
    

    Sequence, based on observed residues (ATOM records):
    >4q2tA (A:)
    asminiisrlqevfghaikaaypdlenppllvtpsqqakfgdyqcnsamgisqmlktkeq
    kvnpreiaenitkhlpdneciekveiagpgfinvhlrkdfvseqltsllvngvqlpalge
    nkkvivdfsspniakemhvghlrstiigesisrlfefagydvlrlnhvgdwgtqfgmlia
    hlqdkfpdyltvsppigdlqvfykeskkrfdteeefkkrayqcvvllqgknpditkawkl
    icdvsrqelnkiydaldvsliergesfyqdrmndivkefedrgfvqvddgrkivfvpgcs
    ipltivksdggytydtsdlaaikqrlfeekadmiiyvvdngqsvhfqtifaaaqmigwyd
    pkvtrvfhagfgvvlgedkkkfktrsgetvrlmdllgeglkrsmdklkekerdkvltaee
    lnaaqtsvaygcikyadlsrnrlndyifsfdkmlddrgntaayllyaftrirsiarlani
    deemlqkaaretkilldhekewklgrcilrfpeilqkilddlflhtlcdyiyelatafte
    fydscycvekdrqtgkilkvnmwrmllceavaavmakgfdilgikpvqrm
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4q2tB (B:)
    hhhhhhssglvprgshmasminiisrlqevfghaikaaypdlenppllvtpsqqakfgdy
    qcnsamgisqmlktkeqkvnpreiaenitkhlpdneciekveiagpgfinvhlrkdfvse
    qltsllvngvqlpalgenkkvivdfsspniakemhvghlrstiigesisrlfefagydvl
    rlnhvgdwgtqfgmliahlqdkfpdyltvsppigdlqvfykeskkrfdteeefkkrayqc
    vvllqgknpditkawklicdvsrqelnkiydaldvsliergesfyqdrmndivkefedrg
    fvqvddgrkivfvpgcsipltivksdggytydtsdlaaikqrlfeekadmiiyvvdngqs
    vhfqtifaaaqmigwydpkvtrvfhagfgvvlgedkkkfktrsgetvrlmdllgeglkrs
    mdklkekerdkvltaeelnaaqtsvaygcikyadlsrnrlndyifsfdkmlddrgntaay
    llyaftrirsiarlanideemlqkaaretkilldhekewklgrcilrfpeilqkilddlf
    lhtlcdyiyelataftefydscycvekdrqtgkilkvnmwrmllceavaavmakgfdilg
    ikpvqrm
    

    Sequence, based on observed residues (ATOM records):
    >4q2tB (B:)
    asminiisrlqevfghaikaaypdlenppllvtpsqqakfgdyqcnsamgisqmlktkeq
    kvnpreiaenitkhlpdneciekveiagpgfinvhlrkdfvseqltsllvngvqlpalge
    nkkvivdfsspniakemhvghlrstiigesisrlfefagydvlrlnhvgdwgtqfgmlia
    hlqdkfpdyltvsppigdlqvfykeskkrfdteeefkkrayqcvvllqgknpditkawkl
    icdvsrqelnkiydaldvsliergesfyqdrmndivkefedrgfvqvddgrkivfvpgcs
    ipltivksdggytydtsdlaaikqrlfeekadmiiyvvdngqsvhfqtifaaaqmigwyd
    pkvtrvfhagfgvvlgedkkkfktretvrlmdllgeglkrsmdklkekerdkvltaeeln
    aaqtsvaygcikyadlsrnrlndyifsfdkmlddrgntaayllyaftrirsiarlanide
    emlqkaaretkilldhekewklgrcilrfpeilqkilddlflhtlcdyiyelataftefy
    dscycvekdrqtgkilkvnmwrmllceavaavmakgfdilgikpvqrm