PDB entry 4pz4

View 4pz4 on RCSB PDB site
Description: High-resolution crystal structure of the human CD44 hyaluronan binding domain in new space group
Class: cell adhesion
Keywords: Link module, Binding protein, Hyaluronan, Ectodomain, CELL ADHESION
Deposited on 2014-03-28, released 2014-09-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-10-15, with a file datestamp of 2014-10-10.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.199
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: CD44 antigen
    Species: Homo sapiens [TaxId:9606]
    Gene: CD44, Cd44 Ly-24, LHR, MDU2, MDU3, MIC4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16070 (0-153)
      • engineered mutation (0-1)
    Domains in SCOPe 2.08: d4pz4a_
  • Chain 'B':
    Compound: CD44 antigen
    Species: Homo sapiens [TaxId:9606]
    Gene: CD44, Cd44 Ly-24, LHR, MDU2, MDU3, MIC4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pz4b_
  • Heterogens: SO4, PEG, GOL, EDO, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4pz4A (A:)
amaqidlnitcrfagvfhvekngrysisrteaadlckafnstlptmaqmekalsigfetc
rygfieghvviprihpnsicaanntgvyiltsntsqydtycfnasappeedctsvtdlpn
afdgpititivnrdgtryvqkgeyrtnpediyps

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4pz4B (B:)
amaqidlnitcrfagvfhvekngrysisrteaadlckafnstlptmaqmekalsigfetc
rygfieghvviprihpnsicaanntgvyiltsntsqydtycfnasappeedctsvtdlpn
afdgpititivnrdgtryvqkgeyrtnpediyps

    Sequence, based on observed residues (ATOM records): (download) 
    >4pz4B (B:)
aqidlnitcrfagvfhvekngrysisrteaadlckafnstlptmaqmekalsigfetcry
gfieghvviprihpnsicaanntgvyiltsntsqydtycfnasappeedctsvtdlpnaf
dgpititivnrdgtryvqkgeyrtnpediyps