PDB entry 4pxz

View 4pxz on RCSB PDB site
Description: crystal structure of p2y12 receptor in complex with 2mesadp
Deposited on 2014-03-25, released 2014-04-30
The last revision was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: P2Y purinoceptor 12, Soluble cytochrome b562
    Species: Homo sapiens [TaxId:9606]
    Gene: HORK3, P2RY12, P2Y12, cybC
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H244 (Start-231)
    • Uniprot P0ABE7 (232-337)
      • engineered mutation (238)
      • engineered mutation (333)
      • engineered mutation (337)
    • Uniprot Q9H244 (338-End)
      • engineered mutation (408)
  • Heterogens: 6AD, CLR, OLC, PEG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4pxzA (A:)
dykddddgapqavdnltsapgntslctrdykitqvlfpllytvlffvglitnglamriff
qirsksnfiiflkntvisdllmiltfpfkilsdaklgtgplrtfvcqvtsvifyftmyis
isflglitidryqkttrpfktsnpknllgakilsvviwafmfllslpnmiltnrqprdkn
vkkcsflksefglvwheivnyicqvifwinflivivcytlitkelyrsyvrtadlednwe
tlndnlkviekadnaaqvkdaltkmraaaldaqkatppkledkspdspemkdfrhgfdil
vgqiddalklanegkvkeaqaaaeqlkttrnayiqkylrgvgkvprkkvnvkvfiiiavf
ficfvpfhfaripytlsqtrdvfdctaentlfyvkestlwltslnaclnpfiyfflcksf
rnslismlkcpnsatslsqdnrkkeqdggdpneetpmgrplevlfq

    Sequence, based on observed residues (ATOM records):
    >4pxzA (A:)
slctrdykitqvlfpllytvlffvglitnglamriffqirsksnfiiflkntvisdllmi
ltfpfkilsdaklgtgplrtfvcqvtsvifyftmyisisflglitidryqkttrppknll
gakilsvviwafmfllslpnmiltnrqprdknvkkcsflksefglvwheivnyicqvifw
inflivivcytlitkelyrsyvrtadlednwetlndnlkviekadnaaqvkdaltkmraa
aldaqkatppkledkspdspemkdfrhgfdilvgqiddalklanegkvkeaqaaaeqlkt
trnayiqkylrgvgkvprkkvnvkvfiiiavfficfvpfhfaripytlsqtrdvfdctae
ntlfyvkestlwltslnaclnpfiyfflcksf