PDB entry 4pwq

View 4pwq on RCSB PDB site
Description: high-resolution crystal structure of the e1-domain of the amyloid precursor protein
Deposited on 2014-03-21, released 2015-02-04
The last revision was dated 2015-02-04, with a file datestamp of 2015-01-30.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.16
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: amyloid beta a4 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: APP, A4, AD1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: amyloid beta a4 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: APP, A4, AD1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4pwqA (A:)
mlevptdgnagllaepqiamfcgrlnmhmnvqngkwdsdpsgtktcidtkegilqycqev
ypelqitnvveanqpvtiqnwckrgrkqckthphfvipyrclvgefvsdallvpdkckfl
hqermdvcethlhwhtvaketcsekstnlhdygmllpcgidkfrgvefvccplaiegrkl
aaalehhhhhh

    Sequence, based on observed residues (ATOM records):
    >4pwqA (A:)
llaepqiamfcgrlnmhmnvqngkwdsdpsgtktcidtkegilqycqevypelqitnvve
anqpvtiqnwckrgrkqckthphfvipyrclvgefvsdallvpdkckflhqermdvceth
lhwhtvaketcsekstnlhdygmllpcgidkfrgvefvccpl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4pwqB (B:)
mlevptdgnagllaepqiamfcgrlnmhmnvqngkwdsdpsgtktcidtkegilqycqev
ypelqitnvveanqpvtiqnwckrgrkqckthphfvipyrclvgefvsdallvpdkckfl
hqermdvcethlhwhtvaketcsekstnlhdygmllpcgidkfrgvefvccplaiegrkl
aaalehhhhhh

    Sequence, based on observed residues (ATOM records):
    >4pwqB (B:)
aepqiamfcgrlnmhmnvqngkwdsdpsgtktcidtkegilqycqevypelqitnvvean
qpvtiqnwckthphfvipyrclvgefvsdallvpdkckflhqermdvcethlhwhtvake
tcsekstnlhdygmllpcgidkfrgvefvccpl