PDB entry 4pwn

View 4pwn on RCSB PDB site
Description: Crystal structure of Active WNK1 kinase
Class: transferase
Keywords: kinase, WNK1, Ser/Thr protein kinase, Serine/Threonine kinase, ATP-binding, phosphorylation, TRANSFERASE
Deposited on 2014-03-20, released 2014-05-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 1.84 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase WNK1
    Species: Homo sapiens [TaxId:9606]
    Gene: WNK1, HSN2, KDP, KIAA0344, PRKWNK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H4A3 (0-273)
      • expression tag (164)
    Domains in SCOPe 2.08: d4pwna_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4pwnA (A:)
kavgmsndgrflkfdieigrgsfktvykgldtettvevawcelqdrkltkserqrfkeea
emlkglqhpnivrfydswestvkgkkcivlvtelmtsgtlktylkrfkvmkikvlrswcr
qilkglqflhtrtppiihrdlkcdnifitgptgsvkigdlglatlekrasfaksvigtpe
fmapemyeekydesvdvyafgmcmlematseypysecqnaaqiyrrvtsgvkpasfdkva
ipevkeiiegcirqnkderysikdllnhaffqee

    Sequence, based on observed residues (ATOM records): (download) 
    >4pwnA (A:)
kavgmsndgrflkfdieigrgsfktvykgldtettvevawcelqdfkeeaemlkglqhpn
ivrfydswestcivlvtelmtsgtlktylkrfkvmkikvlrswcrqilkglqflhtrtpp
iihrdlkcdnifitgptgsvkigdlglatlefmapemyeekydesvdvyafgmcmlemat
seypysecqnaaqiyrrvtsgvkpasfdkvaipevkeiiegcirqnkderysikdllnha
ffqee