PDB entry 4pw5

View 4pw5 on RCSB PDB site
Description: structure of UHRF2-SRA in complex with a 5hmC-containing DNA, complex I
Class: ligase/DNA
Keywords: SRA, 5hmC binding, 5hmC-containing DNA, hydroxymethylation, nuclear, LIGASE-DNA complex
Deposited on 2014-03-18, released 2014-05-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-06-25, with a file datestamp of 2014-06-20.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.163
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 ubiquitin-protein ligase UHRF2
    Species: Homo sapiens [TaxId:9606]
    Gene: UHRF2, NIRF, RNF107
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4pw5a_
  • Chain 'B':
    Compound: E3 ubiquitin-protein ligase UHRF2
    Species: Homo sapiens [TaxId:9606]
    Gene: UHRF2, NIRF, RNF107
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4pw5b_
  • Chain 'C':
    Compound: 5hmC-containing DNA1
  • Chain 'D':
    Compound: 5hmC-containing DNA2
  • Chain 'E':
    Compound: E3 ubiquitin-protein ligase UHRF2
    Species: Homo sapiens [TaxId:9606]
    Gene: UHRF2, NIRF, RNF107
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4pw5e_
  • Chain 'F':
    Compound: E3 ubiquitin-protein ligase UHRF2
    Species: Homo sapiens [TaxId:9606]
    Gene: UHRF2, NIRF, RNF107
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4pw5f_
  • Chain 'G':
    Compound: 5hmC-containing DNA1
  • Chain 'H':
    Compound: 5hmC-containing DNA2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4pw5A (A:)
    stesrrdwgrgmacvgrtrectivpsnhygpipgipvgstwrfrvqvseagvhrphvggi
    hgrsndgayslvlaggfadevdrgdeftytgsggknlagnkrigapsadqtltnmnrala
    lncdaplddkigaesrnwragkpvrvirsfkgrkiskyapeegnrydgiykvvkywpeis
    sshgflvwryllrrddvepapwtsegiersrrlclrlqypagypsdkegk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pw5A (A:)
    ivpsnhygpipgipvgstwrfrvqvseagvhrphvggihgrsndgayslvlaggfadevd
    rgdeftytgsggsadqtltnmnralalncdaplddkigaesrnwragkpvrvirsfkgrk
    iskyapeegnrydgiykvvkywpeissshgflvwryllrrddvepapwtsegiersrrlc
    lrlqypagy
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4pw5B (B:)
    stesrrdwgrgmacvgrtrectivpsnhygpipgipvgstwrfrvqvseagvhrphvggi
    hgrsndgayslvlaggfadevdrgdeftytgsggknlagnkrigapsadqtltnmnrala
    lncdaplddkigaesrnwragkpvrvirsfkgrkiskyapeegnrydgiykvvkywpeis
    sshgflvwryllrrddvepapwtsegiersrrlclrlqypagypsdkegk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pw5B (B:)
    ivpsnhygpipgipvgstwrfrvqvseagvhrphvggihgrsndgayslvlaggfadevd
    rgdeftytgsgsadqtltnmnralalncdaplddkigaesrnwragkpvrvirsfkgrki
    skyapeegnrydgiykvvkywpeissshgflvwryllrrddvepapwtsegiersrrlcl
    rlqypagy
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >4pw5E (E:)
    stesrrdwgrgmacvgrtrectivpsnhygpipgipvgstwrfrvqvseagvhrphvggi
    hgrsndgayslvlaggfadevdrgdeftytgsggknlagnkrigapsadqtltnmnrala
    lncdaplddkigaesrnwragkpvrvirsfkgrkiskyapeegnrydgiykvvkywpeis
    sshgflvwryllrrddvepapwtsegiersrrlclrlqypagypsdkegk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pw5E (E:)
    vpsnhygpipgipvgstwrfrvqvseagvhrphvggihgrsndgayslvlaggfadevdr
    gdeftytgsggsadqtltnmnralalncdaplddkigaesrnwragkpvrvirsfkgrki
    skyapeegnrydgiykvvkywpeissshgflvwryllrrddvepapwtsegiersrrlcl
    rlqypagy
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >4pw5F (F:)
    stesrrdwgrgmacvgrtrectivpsnhygpipgipvgstwrfrvqvseagvhrphvggi
    hgrsndgayslvlaggfadevdrgdeftytgsggknlagnkrigapsadqtltnmnrala
    lncdaplddkigaesrnwragkpvrvirsfkgrkiskyapeegnrydgiykvvkywpeis
    sshgflvwryllrrddvepapwtsegiersrrlclrlqypagypsdkegk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pw5F (F:)
    vpsnhygpipgipvgstwrfrvqvseagvhrphvggihgrsndgayslvlaggfadevdr
    gdeftytgsgsadqtltnmnralalncdaplddkigaesrnwragkpvrvirsfkgrkis
    kyapeegnrydgiykvvkywpeissshgflvwryllrrddvepapwtsegiersrrlclr
    lqypagy
    

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.