PDB entry 4pvz

View 4pvz on RCSB PDB site
Description: Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh2
Class: protein binding
Keywords: ARMADILLO repeated structure, nuclear import adapter, importin beta, NLS-cargos, protein binding
Deposited on 2014-03-18, released 2015-08-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-08-26, with a file datestamp of 2015-08-21.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: importin subunit alpha
    Species: Saccharomyces cerevisiae S288c [TaxId:559292]
    Gene: KAP60, N1606, SRP1, YNL189W
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pvza_
  • Chain 'B':
    Compound: importin subunit alpha
    Species: Saccharomyces cerevisiae S288c [TaxId:559292]
    Gene: KAP60, N1606, SRP1, YNL189W
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pvzb_
  • Chain 'C':
    Compound: Inner nuclear membrane protein HEH2
    Species: Saccharomyces cerevisiae S288c [TaxId:559292]
    Gene: D8035.2, HEH2, YDR458C
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q03281 (5-End)
      • expression tag (2-4)
  • Chain 'D':
    Compound: Inner nuclear membrane protein HEH2
    Species: Saccharomyces cerevisiae S288c [TaxId:559292]
    Gene: D8035.2, HEH2, YDR458C
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4pvzA (A:)
    elpqmtqqlnsddmqeqlsatvkfrqilsrehrppidvviqagvvprlvefmrenqpeml
    qleaawaltniasgtsaqtkvvvdadavplfiqllytgsvevkeqaiwalgnvagdstdy
    rdyvlqcnamepilglfnsnkpslirtatwtlsnlcrgkkpqpdwsvvsqalptlakliy
    smdtetlvdacwaisylsdgpqeaiqavidvripkrlvellshestlvqtpalravgniv
    tgndlqtqvvinagvlpalrlllsspkenikkeacwtisnitagnteqiqavidanlipp
    lvkllevaeyktkkeacwaisnassgglqrpdiirylvsqgcikplcdlleiadnriiev
    tldalenilkmgeadkearglninenadfiekaggmekifncqqnendkiyekaykiiet
    yf
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4pvzB (B:)
    elpqmtqqlnsddmqeqlsatvkfrqilsrehrppidvviqagvvprlvefmrenqpeml
    qleaawaltniasgtsaqtkvvvdadavplfiqllytgsvevkeqaiwalgnvagdstdy
    rdyvlqcnamepilglfnsnkpslirtatwtlsnlcrgkkpqpdwsvvsqalptlakliy
    smdtetlvdacwaisylsdgpqeaiqavidvripkrlvellshestlvqtpalravgniv
    tgndlqtqvvinagvlpalrlllsspkenikkeacwtisnitagnteqiqavidanlipp
    lvkllevaeyktkkeacwaisnassgglqrpdiirylvsqgcikplcdlleiadnriiev
    tldalenilkmgeadkearglninenadfiekaggmekifncqqnendkiyekaykiiet
    yf
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.