PDB entry 4pvo

View 4pvo on RCSB PDB site
Description: Crystal Structure of VIM-2 metallo-beta-lactamase in complex with ML302 and ML302F
Class: hydrolase/hydrolase inhibitor
Keywords: alpha-beta/beta-alpha fold, beta-lactamase, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2014-03-18, released 2014-11-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-02-25, with a file datestamp of 2015-02-20.
Experiment type: XRAY
Resolution: 1.48 Å
R-factor: 0.141
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-lactamase class b vim-2
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: bla-VIM-2, blasVIM-2, blaVIM-2, blaVIM2, VIM-2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4pvoa_
  • Chain 'B':
    Compound: beta-lactamase class b vim-2
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: bla-VIM-2, blasVIM-2, blaVIM-2, blaVIM2, VIM-2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4pvob_
  • Heterogens: ZN, S3C, SVB, FMT, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4pvoA (A:)
gpvdssgeyptvseipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllid
tawgakntaallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlae
vegneipthsleglsssgdavrfgpvelfypgaahstdnlvvyvpsasvlyggcaiyels
rtsagnvadadlaewptsieriqqhypeaqfvipghglpggldllkhttnvvkahtnrsv
ve

    Sequence, based on observed residues (ATOM records): (download) 
    >4pvoA (A:)
eyptvseipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllidtawgakn
taallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlaevegneip
thsleglsssgdavrfgpvelfypgaahstdnlvvyvpsasvlyggcaiyelsrtsagnv
adadlaewptsieriqqhypeaqfvipghglpggldllkhttnvvkahtnr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4pvoB (B:)
gpvdssgeyptvseipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllid
tawgakntaallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlae
vegneipthsleglsssgdavrfgpvelfypgaahstdnlvvyvpsasvlyggcaiyels
rtsagnvadadlaewptsieriqqhypeaqfvipghglpggldllkhttnvvkahtnrsv
ve

    Sequence, based on observed residues (ATOM records): (download) 
    >4pvoB (B:)
eyptvseipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllidtawgakn
taallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlaevegneip
thsleglsssgdavrfgpvelfypgaahstdnlvvyvpsasvlyggcaiyelsrtsagnv
adadlaewptsieriqqhypeaqfvipghglpggldllkhttnvvkahtnrsv