PDB entry 4pvg

View 4pvg on RCSB PDB site
Description: Crystal structure of protein tyrosine phosphatase Shp2 catalytic domain complex with small molecular compound L88N79
Class: Hydrolase
Keywords: Hydrolase
Deposited on 2014-03-17, released 2015-04-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-04-15, with a file datestamp of 2015-04-10.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein phosphatase non-receptor type 11
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN11, PTP2C, SHPTP2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pvga_
  • Heterogens: 2WT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4pvgA (A:)
mtdkvkqgfweefetlqqqeckllysrkegqrqenknknryknilpfdhtrvvlhdgdpn
epvsdyinaniimpefetkcnnskpkksyiatqgclqntvndfwrmvfqensrvivmttk
evergkskcvkywpdeyalkeygvmrvrnvkesaahdytlrelklskvgqgntertvwqy
hfrtwpdhgvpsdpggvldfleevhhkqesimdagpvvvhcsagigrtgtfividilidi
irekgvdcdidvpktiqmvrsqrsgmvqteaqyrfiymavqhyietlqrrlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4pvgA (A:)
fetlqqqeckllysrkegqrqenknknryknilpfdhtrvvlhdgdpnepvsdyinanii
mpeksyiatqgclqntvndfwrmvfqensrvivmttkevergkskcvkywpdeyalkeyg
vmrvrnvkesaahdytlrelklskvgqgntertvwqyhfrtwpdhgvpsdpggvldflee
vhhkqesimdagpvvvhcsagigrtgtfividilidiirekgvdcdidvpktiqmvrsqr
sgmvqteaqyrfiymavqhyietl