PDB entry 4pv7

View 4pv7 on RCSB PDB site
Description: cocrystal structure of dipeptidyl-peptidase 4 with an indole scaffold inhibitor
Deposited on 2014-03-15, released 2015-03-18
The last revision was dated 2015-03-18, with a file datestamp of 2015-03-13.
Experiment type: XRAY
Resolution: 3.24 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dipeptidyl peptidase 4 soluble form
    Species: Homo sapiens [TaxId:9606]
    Gene: ADCP2, CD26, DPP4
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Dipeptidyl peptidase 4 soluble form
    Species: Homo sapiens [TaxId:9606]
    Gene: ADCP2, CD26, DPP4
    Database cross-references and differences (RAF-indexed):
  • Heterogens: CJP

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4pv7A (A:)
hhhhhhdydipttenlyfqgamgssrktytltdylkntyrlklyslrwisdheylykqen
nilvfnaeygnssvflenstfdefghsindysispdgqfilleynyvkqwrhsytasydi
ydlnkrqliteeripnntqwvtwspvghklayvwnndiyvkiepnlpsyritwtgkedii
yngitdwvyeeevfsaysalwwspngtflayaqfndtevplieysfysdeslqypktvrv
pypkagavnptvkffvvntdslssvtnatsiqitapasmligdhylcdvtwatqerislq
wlrriqnysvmdicdydessgrwnclvarqhiemsttgwvgrfrpsephftldgnsfyki
isneegyrhicyfqidkkdctfitkgtwevigiealtsdylyyisneykgmpggrnlyki
qlsdytkvtclscelnpercqyysvsfskeakyyqlrcsgpglplytlhssvndkglrvl
ednsaldkmlqnvqmpskkldfiilnetkfwyqmilpphfdkskkypllldvyagpcsqk
adtvfrlnwatylasteniivasfdgrgsgyqgdkimhainrrlgtfevedqieaarqfs
kmgfvdnkriaiwgwsyggyvtsmvlgsgsgvfkcgiavapvsrweyydsvyterymglp
tpednldhyrnstvmsraenfkqveyllihgtaddnvhfqqsaqiskalvdvgvdfqamw
ytdedhgiasstahqhiythmshfikqcfslp

    Sequence, based on observed residues (ATOM records):
    >4pv7A (A:)
rktytltdylkntyrlklyslrwisdheylykqennilvfnaeygnssvflenstfdefg
hsindysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwvtwsp
vghklayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalwwspn
gtflayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffvvntdslssv
tnatsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdydessgrwnc
lvarqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdctfitk
gtwevigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercqyysv
sfskeakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvqmpskkldfiil
netkfwyqmilpphfdkskkypllldvyagpcsqkadtvfrlnwatylasteniivasfd
grgsgyqgdkimhainrrlgtfevedqieaarqfskmgfvdnkriaiwgwsyggyvtsmv
lgsgsgvfkcgiavapvsrweyydsvyterymglptpednldhyrnstvmsraenfkqve
yllihgtaddnvhfqqsaqiskalvdvgvdfqamwytdedhgiasstahqhiythmshfi
kqcfslp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4pv7B (B:)
hhhhhhdydipttenlyfqgamgssrktytltdylkntyrlklyslrwisdheylykqen
nilvfnaeygnssvflenstfdefghsindysispdgqfilleynyvkqwrhsytasydi
ydlnkrqliteeripnntqwvtwspvghklayvwnndiyvkiepnlpsyritwtgkedii
yngitdwvyeeevfsaysalwwspngtflayaqfndtevplieysfysdeslqypktvrv
pypkagavnptvkffvvntdslssvtnatsiqitapasmligdhylcdvtwatqerislq
wlrriqnysvmdicdydessgrwnclvarqhiemsttgwvgrfrpsephftldgnsfyki
isneegyrhicyfqidkkdctfitkgtwevigiealtsdylyyisneykgmpggrnlyki
qlsdytkvtclscelnpercqyysvsfskeakyyqlrcsgpglplytlhssvndkglrvl
ednsaldkmlqnvqmpskkldfiilnetkfwyqmilpphfdkskkypllldvyagpcsqk
adtvfrlnwatylasteniivasfdgrgsgyqgdkimhainrrlgtfevedqieaarqfs
kmgfvdnkriaiwgwsyggyvtsmvlgsgsgvfkcgiavapvsrweyydsvyterymglp
tpednldhyrnstvmsraenfkqveyllihgtaddnvhfqqsaqiskalvdvgvdfqamw
ytdedhgiasstahqhiythmshfikqcfslp

    Sequence, based on observed residues (ATOM records):
    >4pv7B (B:)
rktytltdylkntyrlklyslrwisdheylykqennilvfnaeygnssvflenstfdefg
hsindysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwvtwsp
vghklayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalwwspn
gtflayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffvvntdslssv
tnatsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdydessgrwnc
lvarqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdctfitk
gtwevigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercqyysv
sfskeakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvqmpskkldfiil
netkfwyqmilpphfdkskkypllldvyagpcsqkadtvfrlnwatylasteniivasfd
grgsgyqgdkimhainrrlgtfevedqieaarqfskmgfvdnkriaiwgwsyggyvtsmv
lgsgsgvfkcgiavapvsrweyydsvyterymglptpednldhyrnstvmsraenfkqve
yllihgtaddnvhfqqsaqiskalvdvgvdfqamwytdedhgiasstahqhiythmshfi
kqcfslp