PDB entry 4pum

View 4pum on RCSB PDB site
Description: tRNA-Guanine Transglycosylase (TGT) Mutant D156N in Complex with 6-Amino-2-(methylamino)-1H,7H,8H-imidazo[4,5-g]quinazolin-8-one
Class: transferase/transferase inhibitor
Keywords: Transferase, Guanine Exchange Enzyme, preQ1, tRNA, transferase-transferase inhibitor complex
Deposited on 2014-03-13, released 2014-07-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 1.93 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Queuine tRNA-ribosyltransferase
    Species: Zymomonas mobilis subsp. mobilis [TaxId:264203]
    Gene: tgt, ZMO0363
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28720
      • engineered mutation (157)
      • see remark 999 (313)
    Domains in SCOPe 2.08: d4puma_
  • Heterogens: ZN, GOL, 2WU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4pumA (A:)
gsmveataqetdrprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpet
vratgadiilgntyhlmlrpgaeriaklgglhsfmgwdrpiltdsggyqvmslssltkqs
eegvtfkshldgsrhmlspersieiqhllgsdivmafnectpypatpsraassmersmrw
akrsrdafdsrkeqaenaalfgiqqgsvfenlrqqsadalaeigfdgyavgglavgegqd
emfrvldfsvpmlpddkphylmgvgkpddivgavergidmfdcvlptrsgrngqaftwdg
pinirnarfsedlkpldsechcavcqkwsrayihhlirageilgamlmtehniafyqqlm
qkirdsisegrfsqfaqdfraryfarns

    Sequence, based on observed residues (ATOM records): (download) 
    >4pumA (A:)
rprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpetvratgadiilgn
tyhlmlrpgaeriaklgglhsfmgwdrpiltdsggyqvmslssltkqseegvtfkshsrh
mlspersieiqhllgsdivmafnectpypatpsraassmersmrwakrsrdafdsrkeqa
enaalfgiqqgsvfenlrqqsadalaeigfdgyavgglavgegqdemfrvldfsvpmlpd
dkphylmgvgkpddivgavergidmfdcvlptrsgrngqaftwdgpinirnarfsedlkp
ldsechcavcqkwsrayihhlirageilgamlmtehniafyqqlmqkirdsisegrfsqf
aqdfraryfa