PDB entry 4psg

View 4psg on RCSB PDB site
Description: Crystal Structure of C.elegans Thymidylate Synthase in complex with an inhibitor N(4)OHdCMP
Class: TRANSFERASE/transferase inhibitor
Keywords: ENZYME, METHYLTRANSFERASE, NUCLEOTIDE BIOSYNTHESIS, PROTEIN DIMER, TRANSFERASE, TRANSFERASE-transferase inhibitor complex
Deposited on 2014-03-07, released 2015-02-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-06-17, with a file datestamp of 2015-06-12.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Caenorhabditis elegans [TaxId:6239]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4psga_
  • Chain 'B':
    Compound: Thymidylate synthase
    Species: Caenorhabditis elegans [TaxId:6239]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4psgb_
  • Heterogens: NOH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4psgA (A:)
mevmnkeniiadapsdvvktvqqqvhlnqdeykylkqveqilregtrrddrtgtgtisif
gmqskyclrngtipllttkrvywkgvleellwfisgstdgkllmeknvkiwekngdrafl
dnlgftsreegdlgpvygfqwrhfgakyvdchtdysgqgvdqlaevirqikeqpdsrrii
msawnpsdlgqmvlppchtmcqfyvdngelscqlyqrsgdmglgvpfnlasygllthmia
kvcglkpgtlvhtlgdahvysnhvdalkiqldrepyafpkirftrdvasiddftsdmial
ddykchpkipmdmav

    Sequence, based on observed residues (ATOM records): (download) 
    >4psgA (A:)
qvhlnqdeykylkqveqilregtrrddrtgtgtisifgmqskyclrngtipllttkrvyw
kgvleellwfisgstdgkllmeknvkiwekngdrafldnlgftsreegdlgpvygfqwrh
fgakyvdchtdysgqgvdqlaevirqikeqpdsrriimsawnpsdlgqmvlppchtmcqf
yvdngelscqlyqrsgdmglgvpfnlasygllthmiakvcglkpgtlvhtlgdahvysnh
vdalkiqldrepyafpkirftrdvasiddftsdmialddykchpkipmd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4psgB (B:)
mevmnkeniiadapsdvvktvqqqvhlnqdeykylkqveqilregtrrddrtgtgtisif
gmqskyclrngtipllttkrvywkgvleellwfisgstdgkllmeknvkiwekngdrafl
dnlgftsreegdlgpvygfqwrhfgakyvdchtdysgqgvdqlaevirqikeqpdsrrii
msawnpsdlgqmvlppchtmcqfyvdngelscqlyqrsgdmglgvpfnlasygllthmia
kvcglkpgtlvhtlgdahvysnhvdalkiqldrepyafpkirftrdvasiddftsdmial
ddykchpkipmdmav

    Sequence, based on observed residues (ATOM records): (download) 
    >4psgB (B:)
qvhlnqdeykylkqveqilregtrrddrtgtgtisifgmqskyclrngtipllttkrvyw
kgvleellwfisgstdgkllmeknvkiwekngdrafldnlgftsreegdlgpvygfqwrh
fgakyvdchtdysgqgvdqlaevirqikeqpdsrriimsawnpsdlgqmvlppchtmcqf
yvdngelscqlyqrsgdmglgvpfnlasygllthmiakvcglkpgtlvhtlgdahvysnh
vdalkiqldrepyafpkirftrdvasiddftsdmialddykchpkipmd