PDB entry 4prz

View 4prz on RCSB PDB site
Description: Caspase-8 specific unnatural amino acid peptides
Class: hydrolase/hydrolase inhibitor
Keywords: protease, hydrolase-hydrolase inhibitor complex
Deposited on 2014-03-06, released 2015-01-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-01-21, with a file datestamp of 2015-01-16.
Experiment type: XRAY
Resolution: 2.12 Å
R-factor: 0.191
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: caspase-8
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP8, CASP8 MCH5, MCH5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4prza_
  • Chain 'B':
    Compound: (ace)let(1u8) peptide
    Database cross-references and differences (RAF-indexed):
    • PDB 4PRZ (Start-3)
  • Heterogens: DTD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4przA (A:)
msesqtldkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfe
elhfeikphddctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiye
ltsqftglkcpslagkpkvffiqacqgdnyqkgipvetdseeqpylemdlsspqtryipd
eadfllgmatvnncvsyrnpaegtwyiqslcqslrercprgddiltiltevnyevsnkdd
kknmgkqmpqptftlrkklvfpsdaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4przA (A:)
dkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfeelhfeik
phddctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiyeltsqftg
lkcpslagkpkvffiqacqgdnyqkgipvettryipdeadfllgmatvnncvsyrnpaeg
twyiqslcqslrercprgddiltiltevnyevsnkddkknmgkqmpqptftlrkklvfps

  • Chain 'B':
    No sequence available.