PDB entry 4prh

View 4prh on RCSB PDB site
Description: crystal structure of tk3 tcr-hla-b*35:08-hpvg-d5 complex
Deposited on 2014-03-05, released 2014-04-30
The last revision was dated 2014-07-02, with a file datestamp of 2014-06-27.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.214
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: MHC class I antigen
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-B
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (3-99)
      • conflict (46)
  • Chain 'C':
    Compound: Epstein-Barr nuclear antigen 1
    Species: HUMAN HERPESVIRUS 4, synthetic [TaxId:10376]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: TK3 TCR alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PRH
  • Chain 'E':
    Compound: TK3 TCR beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PRH (Start-242)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4prhA (A:)
shsmryfytamsrpgrgeprfiavgyvddtqfvrfdsdaasprteprapwieqegpeywd
rntqifktntqtyreslrnlrgyynqseagshiiqrmygcdlgpdgrllrghdqsaydgk
dyialnedlsswtaadtaaqitqrkweaarvaeqrrayleglcvewlrrylengketlqr
adppkthvthhpvsdheatlrcwalgfypaeitltwqrdgedqdtelvetrpagdrtfqk
waavvvpsgeeqrytchvqheglpkpltlrwe

    Sequence, based on observed residues (ATOM records):
    >4prhA (A:)
shsmryfytamsrpgrgeprfiavgyvddtqfvrfdsdaasprteprapwieqegpeywd
rntqifktntqtyreslrnlrgyynqseagshiiqrmygcdlgpdgrllrghdqsaydgk
dyialnedlsswtaadtaaqitqrkweaarvaeqrrayleglcvewlrrylengketlqr
adppkthvlrcwalgfypaeitltqdtelvetrpagdrtfqkwchvqheglpkpltlrwe

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4prhB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngerlekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records):
    >4prhB (B:)
rtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngerlekvehsdlsfskdwsf
yllyytefvnhvtlsqpkivkwdrdm

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >4prhC (C:)
hpvgdadyfey

  • Chain 'D':
    Sequence, based on SEQRES records:
    >4prhD (D:)
hmedqvtqspealrlqegessslncsytvsglrglfwyrqdpgkgpeflftlysageeke
kerlkatltkkesflhitapkpedsatylcavqdlgtsgsrltfgegtqltvnpniqnpd
pavyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavaws
nksdfacanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records):
    >4prhD (D:)
edqvtqspealrlqegessslncsytvsglrglfwyrqdpgkgpeflftlysageekeke
rlkatltkkesflhitapkpedsatylcavqdlgtsgsrltfgegtqltvnpniqnpdpa
vyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnk
sdfacanafnnsiipedtffps

  • Chain 'E':
    Sequence, based on SEQRES records:
    >4prhE (E:)
hmdsgvtqtpkhlitatgqrvtlrcsprsgdlsvywyqqsldqglqfliqyyngeerakg
nilerfsaqqfpdlhselnlsslelgdsalyfcassarsgelffgegsrltvledlknvf
ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
rad

    Sequence, based on observed residues (ATOM records):
    >4prhE (E:)
sgvtqtpkhlitatgqrvtlrcsprsgdlsvywyqqsldqglqfliqyyngeerakgnil
erfsaqqfpdlhselnlsslelgdsalyfcassarsgelffgegsrltvledlknvfppe
vavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpaln
dsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgrad