PDB entry 4pqt

View 4pqt on RCSB PDB site
Description: Insights into the mechanism of deubiquitination by JAMM deubiquitinases from co-crystal structures of enzyme with substrate and product
Class: Hydrolase/transcription
Keywords: helix-beta-helix sandwich, ubiquitin, deubiquitination, Zinc metalloprotease, Lysine 63-linked polyubiquitin, Hydrolase-transcription complex
Deposited on 2014-03-04, released 2014-06-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-06-18, with a file datestamp of 2014-06-13.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.204
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: AMSH-like protease sst2
    Species: Schizosaccharomyces pombe [TaxId:284812]
    Gene: SPAC19B12.10, sst2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9P371
      • engineered mutation (115)
  • Chain 'B':
    Compound: Protein UBBP4
    Species: Homo sapiens [TaxId:9606]
    Gene: UBBP4, Ubiquitin
    Database cross-references and differences (RAF-indexed):
    • Uniprot J3QRK5 (5-80)
      • conflict (59)
    Domains in SCOPe 2.07: d4pqtb_
  • Heterogens: ZN, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4pqtB (B:)
    gplgsmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrt
    lsdyniqkestlhlvlrlrgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pqtB (B:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgg