PDB entry 4pq7

View 4pq7 on RCSB PDB site
Description: The crystal structure of the human carbonic anhydrase ii in complex with a sulfamide inhibitor
Class: Lyase/lyase Inhibitor
Keywords: SULFAMIDE, zinc binding, Lyase-lyase Inhibitor complex
Deposited on 2014-02-28, released 2014-10-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-10-08, with a file datestamp of 2014-10-03.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.156
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00918 (2-End)
      • expression tag (1)
    Domains in SCOPe 2.08: d4pq7a1, d4pq7a2
  • Heterogens: ZN, IL3, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4pq7A (A:)
mgmshhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslr
ilnnghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaael
hlvhwntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnf
dprgllpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepee
lmvdnwrpaqplknrqikasfk

    Sequence, based on observed residues (ATOM records): (download) 
    >4pq7A (A:)
gmshhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslri
lnnghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelh
lvhwntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfd
prgllpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeel
mvdnwrpaqplknrqikasf