PDB entry 4ppp

View 4ppp on RCSB PDB site
Description: Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Fluoro-Resveratrol
Deposited on 2014-02-27, released 2014-05-07
The last revision was dated 2014-06-11, with a file datestamp of 2014-06-06.
Experiment type: XRAY
Resolution: 2.69 Å
R-factor: 0.205
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR, ESR1, NR3A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372 (0-243)
      • engineered mutation (232)
  • Chain 'B':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR, ESR1, NR3A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372 (Start-243)
      • engineered mutation (232)
  • Chain 'C':
    Compound: nuclear receptor coactivator 2
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: nuclear receptor coactivator 2
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: FSV, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4pppA (A:)
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdllleml
dahr

    Sequence, based on observed residues (ATOM records):
    >4pppA (A:)
slalsltadqmvsalldaeppilysefseasmmglltnladrelvhminwakrvpgfvdl
tlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmlla
tssrfrmmnlqgeefvclksiillnsgvytfkdhihrvldkitdtlihlmakagltlqqq
hqrlaqlllilshirhmsnkgmehlysmkcknvvplsdlllemldahr

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4pppB (B:)
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdllleml
dahr

    Sequence, based on observed residues (ATOM records):
    >4pppB (B:)
sltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvpgfv
dltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdml
latssrfrmmnlqgeefvclksiillnsgvytfksleekdhihrvldkitdtlihlmaka
gltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdlllemldahr

  • Chain 'C':
    Sequence, based on SEQRES records:
    >4pppC (C:)
kilhrllqd

    Sequence, based on observed residues (ATOM records):
    >4pppC (C:)
kilhrll

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >4pppD (D:)
kilhrllqd