PDB entry 4pom

View 4pom on RCSB PDB site
Description: Crystal structures of thioredoxin with mesna at 1.85A resolution
Class: oxidoreductase
Keywords: oxidoreductase
Deposited on 2014-02-26, released 2014-10-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-03-18, with a file datestamp of 2015-03-13.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thioredoxin
    Species: Homo sapiens [TaxId:9606]
    Gene: TXN, TRDX, TRX, TRX1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10599 (4-108)
      • expression tag (2-3)
      • engineered mutation (16)
      • engineered mutation (19)
      • engineered mutation (98)
      • engineered mutation (106)
    Domains in SCOPe 2.08: d4poma1, d4poma2
  • Chain 'B':
    Compound: thioredoxin
    Species: Homo sapiens [TaxId:9606]
    Gene: TXN, TRDX, TRX, TRX1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10599 (4-108)
      • expression tag (2-3)
      • engineered mutation (16)
      • engineered mutation (19)
      • engineered mutation (98)
      • engineered mutation (106)
    Domains in SCOPe 2.08: d4pomb1, d4pomb2
  • Chain 'C':
    Compound: thioredoxin
    Species: Homo sapiens [TaxId:9606]
    Gene: TXN, TRDX, TRX, TRX1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10599 (4-108)
      • expression tag (2-3)
      • engineered mutation (16)
      • engineered mutation (19)
      • engineered mutation (98)
      • engineered mutation (106)
    Domains in SCOPe 2.08: d4pomc1, d4pomc2
  • Chain 'D':
    Compound: thioredoxin
    Species: Homo sapiens [TaxId:9606]
    Gene: TXN, TRDX, TRX, TRX1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10599 (4-108)
      • expression tag (2-3)
      • engineered mutation (16)
      • engineered mutation (19)
      • engineered mutation (98)
      • engineered mutation (106)
    Domains in SCOPe 2.08: d4pomd1, d4pomd2
  • Heterogens: COM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4pomA (A:)
gagtmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnvifle
vdvddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv

    Sequence, based on observed residues (ATOM records): (download) 
    >4pomA (A:)
gtmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnviflevd
vddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4pomB (B:)
gagtmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnvifle
vdvddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv

    Sequence, based on observed residues (ATOM records): (download) 
    >4pomB (B:)
gtmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnviflevd
vddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4pomC (C:)
gagtmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnvifle
vdvddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv

    Sequence, based on observed residues (ATOM records): (download) 
    >4pomC (C:)
gtmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnviflevd
vddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4pomD (D:)
gagtmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnvifle
vdvddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv

    Sequence, based on observed residues (ATOM records): (download) 
    >4pomD (D:)
gtmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnviflevd
vddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv