PDB entry 4pok

View 4pok on RCSB PDB site
Description: Crystal structures of thioredoxin with mesna at 2.5A resolution
Class: oxidoreductase
Keywords: oxidoreductase
Deposited on 2014-02-25, released 2014-10-29
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-10-29, with a file datestamp of 2014-10-24.
Experiment type: XRAY
Resolution: 2.52 Å
R-factor: 0.238
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thioredoxin
    Species: Homo sapiens [TaxId:9606]
    Gene: TXN, TRDX, TRX, TRX1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10599 (4-108)
      • expression tag (3)
      • engineered mutation (16)
      • engineered mutation (19)
      • engineered mutation (98)
      • engineered mutation (106)
    Domains in SCOPe 2.05: d4poka_
  • Chain 'B':
    Compound: thioredoxin
    Species: Homo sapiens [TaxId:9606]
    Gene: TXN, TRDX, TRX, TRX1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10599 (4-108)
      • expression tag (3)
      • engineered mutation (16)
      • engineered mutation (19)
      • engineered mutation (98)
      • engineered mutation (106)
    Domains in SCOPe 2.05: d4pokb_
  • Chain 'C':
    Compound: thioredoxin
    Species: Homo sapiens [TaxId:9606]
    Gene: TXN, TRDX, TRX, TRX1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10599 (4-108)
      • expression tag (3)
      • engineered mutation (16)
      • engineered mutation (19)
      • engineered mutation (98)
      • engineered mutation (106)
    Domains in SCOPe 2.05: d4pokc_
  • Chain 'D':
    Compound: thioredoxin
    Species: Homo sapiens [TaxId:9606]
    Gene: TXN, TRDX, TRX, TRX1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10599 (4-108)
      • expression tag (3)
      • engineered mutation (16)
      • engineered mutation (19)
      • engineered mutation (98)
      • engineered mutation (106)
    Domains in SCOPe 2.05: d4pokd_
  • Heterogens: COM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4pokA (A:)
gagtmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnvifle
vdvddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv

    Sequence, based on observed residues (ATOM records): (download) 
    >4pokA (A:)
tmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnviflevdv
ddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4pokB (B:)
gagtmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnvifle
vdvddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv

    Sequence, based on observed residues (ATOM records): (download) 
    >4pokB (B:)
tmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnviflevdv
ddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4pokC (C:)
gagtmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnvifle
vdvddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv

    Sequence, based on observed residues (ATOM records): (download) 
    >4pokC (C:)
tmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnviflevdv
ddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4pokD (D:)
gagtmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnvifle
vdvddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv

    Sequence, based on observed residues (ATOM records): (download) 
    >4pokD (D:)
tmvkqiesktafqkalkaagdklvvvdfsatwcgpckmikpffhslsekysnviflevdv
ddcqdvasecevkcmptfqffkkgqkvgefsgankkkleatinklv