PDB entry 4po2

View 4po2 on RCSB PDB site
Description: Crystal Structure of the Stress-Inducible Human Heat Shock Protein HSP70 Substrate-Binding Domain in Complex with Peptide Substrate
Deposited on 2014-02-24, released 2014-08-20
The last revision was dated 2014-08-20, with a file datestamp of 2014-08-15.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.177
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock 70 kDa protein 1A/1B
    Species: Homo sapiens [TaxId:9606]
    Gene: HSPA1, HSPA1A, HSPA1B, HSX70
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Heat shock 70 kDa protein 1A/1B
    Species: Homo sapiens [TaxId:9606]
    Gene: HSPA1, HSPA1A, HSPA1B, HSX70
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: HSP70 substrate peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 4PO2 (0-6)
  • Chain 'D':
    Compound: HSP70 substrate peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 4PO2 (0-6)
  • Heterogens: SO4, PO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4po2A (A:)
mhhhhhhenvqdlllldvaplslgletaggvmtalikrnstiptkqtqifttysdnqpgv
liqvyegeramtkdnnllgrfelsgippaprgvpqievtfdidangilnvtatdkstgka
nkititndkgrlskeeiermvqeaekykaedevqrervsaknalesyafnmksavedegl
kgkiseadkkkvldkcqeviswldantlaekdefehkrkeleqvcnpiisglyqg

    Sequence, based on observed residues (ATOM records):
    >4po2A (A:)
envqdlllldvaplslgletaggvmtalikrnstiptkqtqifttysdnqpgvliqvyeg
eramtkdnnllgrfelsgippaprgvpqievtfdidangilnvtatdkstgkankititn
dkgrlskeeiermvqeaekykaedevqrervsaknalesyafnmksavedeglkgkisea
dkkkvldkcqeviswldantlaekdefehkrkeleqvcnpiisglyqg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4po2B (B:)
mhhhhhhenvqdlllldvaplslgletaggvmtalikrnstiptkqtqifttysdnqpgv
liqvyegeramtkdnnllgrfelsgippaprgvpqievtfdidangilnvtatdkstgka
nkititndkgrlskeeiermvqeaekykaedevqrervsaknalesyafnmksavedegl
kgkiseadkkkvldkcqeviswldantlaekdefehkrkeleqvcnpiisglyqg

    Sequence, based on observed residues (ATOM records):
    >4po2B (B:)
dvaplslgletaggvmtalikrnstiptkqtqifttysdnqpgvliqvyegeramtkdnn
llgrfelsgippaprgvpqievtfdidangilnvtatdkstgkankititnlskeeierm
vqeaekykaedevqrervsaknalesyafnmksavedeglkgkiseadkkkvldkcqevi
swldantlaekdefehkrkeleqvcnpiisglyqg

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >4po2C (C:)
nrllltg

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >4po2D (D:)
nrllltg