PDB entry 4pns

View 4pns on RCSB PDB site
Description: Crystal Structure of human Tankyrase 2 in complex with INH2BP.
Deposited on 2014-05-25, released 2014-10-15
The last revision was dated 2015-01-07, with a file datestamp of 2015-01-02.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: 0.189
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tankyrase-2
    Species: Homo sapiens [TaxId:9606]
    Gene: TNKS2, PARP5B, TANK2, TNKL
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: tankyrase-2
    Species: Homo sapiens [TaxId:9606]
    Gene: TNKS2, PARP5B, TANK2, TNKL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H2K2
      • expression tag (16-20)
  • Chain 'C':
    Compound: tankyrase-2
    Species: Homo sapiens [TaxId:9606]
    Gene: TNKS2, PARP5B, TANK2, TNKL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H2K2 (21-End)
      • expression tag (15-20)
  • Chain 'D':
    Compound: tankyrase-2
    Species: Homo sapiens [TaxId:9606]
    Gene: TNKS2, PARP5B, TANK2, TNKL
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, 32Y, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4pnsA (A:)
mgsshhhhhhssgrenlyfqgspddkefqsveeemqstvrehrdgghaggifnrynilki
qkvcnkklwerythrrkevseenhnhanermlfhgspfvnaiihkgfderhayiggmfga
giyfaenssksnqyvygigggtgcpvhkdrscyichrqllfcrvtlgksflqfsamkmah
sppghhsvtgrpsvnglalaeyviyrgeqaypeylityqimrpegmv

    Sequence, based on observed residues (ATOM records):
    >4pnsA (A:)
dkefqsveeemqstvrehrdgghaggifnrynilkiqkvcnkklwerythrrkevseenh
nhanermlfhgspfvnaiihkgfderhaggmfgagiyfaenssksnqyvygigggtgcpv
hkdrscyichrqllfcrvtlgksflqfsamkmahsppghhsvtgrpsvnglalaeyviyr
geqaypeylityqimrp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4pnsB (B:)
mgsshhhhhhssgrenlyfqgspddkefqsveeemqstvrehrdgghaggifnrynilki
qkvcnkklwerythrrkevseenhnhanermlfhgspfvnaiihkgfderhayiggmfga
giyfaenssksnqyvygigggtgcpvhkdrscyichrqllfcrvtlgksflqfsamkmah
sppghhsvtgrpsvnglalaeyviyrgeqaypeylityqimrpegmv

    Sequence, based on observed residues (ATOM records):
    >4pnsB (B:)
lyfqgdkefqsveeemqstvrehrdgghaggifnrynilkiqkvcnkklwerythrrkev
seenhnhanermlfhgspfvnaiihkgfderhayggmfgagiyfaenssksnqyvygigg
gtgcpvhkdrscyichrqllfcrvtlgksflqfsamkmahsppghhsvtgrpglalaeyv
iyrgeqaypeylityqimrp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >4pnsC (C:)
mgsshhhhhhssgrenlyfqgspddkefqsveeemqstvrehrdgghaggifnrynilki
qkvcnkklwerythrrkevseenhnhanermlfhgspfvnaiihkgfderhayiggmfga
giyfaenssksnqyvygigggtgcpvhkdrscyichrqllfcrvtlgksflqfsamkmah
sppghhsvtgrpsvnglalaeyviyrgeqaypeylityqimrpegmv

    Sequence, based on observed residues (ATOM records):
    >4pnsC (C:)
nlyfqgspddkefqsveeemqstvrehrdgghaggifnrynilkiqkvcnkklwerythr
rkevseenhnhanermlfhgspfvnaiihkgfderhayiggmfgagiyfaenssksnqyv
ygigggtgcpvhkdrscyichrqllfcrvtlgksflqfsamkmahsppghhsvtgrpsvn
glalaeyviyrgeqaypeylityqimrp

  • Chain 'D':
    Sequence, based on SEQRES records:
    >4pnsD (D:)
mgsshhhhhhssgrenlyfqgspddkefqsveeemqstvrehrdgghaggifnrynilki
qkvcnkklwerythrrkevseenhnhanermlfhgspfvnaiihkgfderhayiggmfga
giyfaenssksnqyvygigggtgcpvhkdrscyichrqllfcrvtlgksflqfsamkmah
sppghhsvtgrpsvnglalaeyviyrgeqaypeylityqimrpegmv

    Sequence, based on observed residues (ATOM records):
    >4pnsD (D:)
fqsveeemqstvrehrdgghaggifnrynilkiqkvcnkklwerythrrkevseenhnha
nermlfhgspfvnaiihkgfderhayiggmfgagiyfaenssksnqyvygigggtgcpvh
kdrscyichrqllfcrvtlgksflqfsamkmahsppghhsvtgrplaeyviyrgeqaype
ylityqimrp