PDB entry 4pme
View 4pme on RCSB PDB site
Description: Human transthyretin (TTR) complexed with ferulic acid and curcumin.
Class: Thyroid hormone-binding protein
Keywords: Human transthyretin (TTR) complexes, solubilization of hydrophobic ligands, curcumin degradation, Thyroid hormone-binding protein
Deposited on
2014-05-21, released
2014-10-08
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-11-22, with a file datestamp of
2017-11-17.
Experiment type: XRAY
Resolution: 1.26 Å
R-factor: N/A
AEROSPACI score: 0.61
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4pmea_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4pmeb_ - Heterogens: CUR, NA, EDO, FER, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4pmeA (A:)
kcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegi
ykveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnpk
Sequence, based on observed residues (ATOM records): (download)
>4pmeA (A:)
kcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegi
ykveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4pmeB (B:)
kcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegi
ykveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnpk
Sequence, based on observed residues (ATOM records): (download)
>4pmeB (B:)
kcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegi
ykveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn