PDB entry 4plc

View 4plc on RCSB PDB site
Description: crystal structure of ancestral apicomplexan lactate dehydrogenase with malate.
Deposited on 2014-05-16, released 2014-07-02
The last revision was dated 2019-12-25, with a file datestamp of 2019-12-20.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: lactate dehydrogenase
    Species: Apicomplexa [TaxId:5794]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PLC
  • Chain 'B':
    Compound: lactate dehydrogenase
    Species: Apicomplexa [TaxId:5794]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PLC
  • Chain 'C':
    Compound: lactate dehydrogenase
    Species: Apicomplexa [TaxId:5794]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PLC
  • Chain 'D':
    Compound: lactate dehydrogenase
    Species: Apicomplexa [TaxId:5794]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PLC
  • Heterogens: PYR, NAI, NAD, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4plcA (A:)
mtgtmtkrkkisligsgmiggtmaylcaqkelgdvvlfdvvknmpqgkaldlshsssiad
tnvkvtgtnsyedikgsdvviitagltkapgksdkewsrddllpfnakimrevgenikky
cpnafvivitnpldvmvkvlhehsglpknkvcgmagvldssrfrhfiaeklnvsprdvqa
mvigahgdkmvpltryvtvngiplqefikkgritqeeideivertknaggeivnllgqgs
ayfapaasaiemaeaylkdkkrvlvcscylegqyghkdmfvgvpaviggngvekvielel
tpeekelfdksveevrklqkaikalglehhhhhh

    Sequence, based on observed residues (ATOM records):
    >4plcA (A:)
mtkrkkisligsgmiggtmaylcaqkelgdvvlfdvvknmpqgkaldlshsssiadtnvk
vtgtnsyedikgsdvviitagltkapgksdkewsrddllpfnakimrevgenikkycpna
fvivitnpldvmvkvlhehsglpknkvcgmagvldssrfrhfiaeklnvsprdvqamvig
ahgdkmvpltryvtvngiplqefikkgritqeeideivertknaggeivnllgqgsayfa
paasaiemaeaylkdkkrvlvcscylegqyghkdmfvgvpaviggngvekvieleltpee
kelfdksveevrklqkaikalgle

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4plcB (B:)
mtgtmtkrkkisligsgmiggtmaylcaqkelgdvvlfdvvknmpqgkaldlshsssiad
tnvkvtgtnsyedikgsdvviitagltkapgksdkewsrddllpfnakimrevgenikky
cpnafvivitnpldvmvkvlhehsglpknkvcgmagvldssrfrhfiaeklnvsprdvqa
mvigahgdkmvpltryvtvngiplqefikkgritqeeideivertknaggeivnllgqgs
ayfapaasaiemaeaylkdkkrvlvcscylegqyghkdmfvgvpaviggngvekvielel
tpeekelfdksveevrklqkaikalglehhhhhh

    Sequence, based on observed residues (ATOM records):
    >4plcB (B:)
mtkrkkisligsgmiggtmaylcaqkelgdvvlfdvvknmpqgkaldlshsssiadtnvk
vtgtnsyedikgsdvviitagltkapgksdkewsrddllpfnakimrevgenikkycpna
fvivitnpldvmvkvlhehsglpknkvcgmagvldssrfrhfiaeklnvsprdvqamvig
ahgdkmvpltryvtvngiplqefikkgritqeeideivertknaggeivnllgqgsayfa
paasaiemaeaylkdkkrvlvcscylegqyghkdmfvgvpaviggngvekvieleltpee
kelfdksveevrklqkaikalgle

  • Chain 'C':
    Sequence, based on SEQRES records:
    >4plcC (C:)
mtgtmtkrkkisligsgmiggtmaylcaqkelgdvvlfdvvknmpqgkaldlshsssiad
tnvkvtgtnsyedikgsdvviitagltkapgksdkewsrddllpfnakimrevgenikky
cpnafvivitnpldvmvkvlhehsglpknkvcgmagvldssrfrhfiaeklnvsprdvqa
mvigahgdkmvpltryvtvngiplqefikkgritqeeideivertknaggeivnllgqgs
ayfapaasaiemaeaylkdkkrvlvcscylegqyghkdmfvgvpaviggngvekvielel
tpeekelfdksveevrklqkaikalglehhhhhh

    Sequence, based on observed residues (ATOM records):
    >4plcC (C:)
mtkrkkisligsgmiggtmaylcaqkelgdvvlfdvvknmpqgkaldlshsssiadtnvk
vtgtnsyedikgsdvviitagltkapgksdkewsrddllpfnakimrevgenikkycpna
fvivitnpldvmvkvlhehsglpknkvcgmagvldssrfrhfiaeklnvsprdvqamvig
ahgdkmvpltryvtvngiplqefikkgritqeeideivertknaggeivnllgqgsayfa
paasaiemaeaylkdkkrvlvcscylegqyghkdmfvgvpaviggngvekvieleltpee
kelfdksveevrklqkaikalgle

  • Chain 'D':
    Sequence, based on SEQRES records:
    >4plcD (D:)
mtgtmtkrkkisligsgmiggtmaylcaqkelgdvvlfdvvknmpqgkaldlshsssiad
tnvkvtgtnsyedikgsdvviitagltkapgksdkewsrddllpfnakimrevgenikky
cpnafvivitnpldvmvkvlhehsglpknkvcgmagvldssrfrhfiaeklnvsprdvqa
mvigahgdkmvpltryvtvngiplqefikkgritqeeideivertknaggeivnllgqgs
ayfapaasaiemaeaylkdkkrvlvcscylegqyghkdmfvgvpaviggngvekvielel
tpeekelfdksveevrklqkaikalglehhhhhh

    Sequence, based on observed residues (ATOM records):
    >4plcD (D:)
mtkrkkisligsgmiggtmaylcaqkelgdvvlfdvvknmpqgkaldlshsssiadtnvk
vtgtnsyedikgsdvviitagltkapgksdkewsrddllpfnakimrevgenikkycpna
fvivitnpldvmvkvlhehsglpknkvcgmagvldssrfrhfiaeklnvsprdvqamvig
ahgdkmvpltryvtvngiplqefikkgritqeeideivertknaggeivnllgqgsayfa
paasaiemaeaylkdkkrvlvcscylegqyghkdmfvgvpaviggngvekvieleltpee
kelfdksveevrklqkaikalgle