PDB entry 4pkq

View 4pkq on RCSB PDB site
Description: Anthrax toxin lethal factor with bound zinc
Class: hydrolase
Keywords: Anthrax toxin, lethal factor, metalloproteinase, metalloprotease, structural dynamics, ligand-induced conformational change, HYDROLASE
Deposited on 2014-05-15, released 2014-11-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-27, with a file datestamp of 2017-09-22.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lethal Factor
    Species: Bacillus anthracis [TaxId:1392]
    Gene: lef, pXO1-107, BXA0172, GBAA_pXO1_0172
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15917 (Start-514)
      • engineered mutation (4)
      • expression tag (515-516)
    Domains in SCOPe 2.07: d4pkqa1, d4pkqa2, d4pkqa3
  • Heterogens: ZN, PGE, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4pkqA (A:)
    snalsryekwekikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkr
    iqidssdflsteekeflkklqidirdslseeekellnriqvdssnplsekekeflkklkl
    diqpydinqrlqdtgglidspsinldvrkqykrdiqnidallhqsigstlynkiylyenm
    ninnltatlgadlvdstdntkinrgifnefkknfkysissnymivdinerpaldnerlkw
    riqlspdtragylengklilqrnigleikdvqiikqsekeyiridakvvpkskidtkiqe
    aqlninqewnkalglpkytklitfnvhnryasnivesaylilnewknniqsdlikkvtny
    lvdgngrfvftditlpniaeqythqdeiyeqvhskglyvpesrsillhgpskgvelrnds
    egfihefghavddyagylldknqsdlvtnskkfidifkeegsnltsygrtneaeffaeaf
    rlmhstdhaerlkvqknapktfqfindqikfiinslvpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >4pkqA (A:)
    sryekwekikqhyqhwsdslseegrgllkklqipiepkkddiihslsqeekellkriqid
    ssdflsteekeflkklqidirdslseeekellnriqvdssnplsekekeflkklkldiqp
    ydinqrlqdtgglidspsinldvrkqykrdiqnidallhqsigstlynkiylyenmninn
    ltatlgadlvdstdntkinrgifnefkknfkysissnymivdinerpaldnerlkwriql
    spdtragylengklilqrnigleikdvqiikqsekeyiridakvvpkskidtkiqeaqln
    inqewnkalglpkytklitfnvhnryasnivesaylilnewknniqsdlikkvtnylvdg
    ngrfvftditlpniaeqythqdeiyeqvhskglyvpesrsillhgpskgvelrndsegfi
    hefghavddyagylldknqsdlvtnskkfidifkeegsnltsygrtneaeffaeafrlmh
    stdhaerlkvqknapktfqfindqikfiinslv