PDB entry 4pja

View 4pja on RCSB PDB site
Description: Structure of human MR1-5-OP-RU in complex with human MAIT B-B10 TCR
Class: immune system
Keywords: MR1, TCR, Immune complex, 5-OP-RU, IMMUNE SYSTEM
Deposited on 2014-05-12, released 2014-07-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-10-01, with a file datestamp of 2014-09-26.
Experiment type: XRAY
Resolution: 2.68 Å
R-factor: 0.172
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-End)
      • initiating methionine (0)
      • engineered mutation (261)
    Domains in SCOPe 2.07: d4pjaa1, d4pjaa2, d4pjaa3
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4pjab_
  • Chain 'C':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-End)
      • initiating methionine (0)
      • engineered mutation (261)
    Domains in SCOPe 2.07: d4pjac1, d4pjac2, d4pjac3
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4pjad_
  • Chain 'E':
    Compound: TCR-alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PJA
    Domains in SCOPe 2.07: d4pjae1, d4pjae2
  • Chain 'F':
    Compound: TCR-beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PJA
    Domains in SCOPe 2.07: d4pjaf1, d4pjaf2
  • Chain 'G':
    Compound: TCR-alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PJA
    Domains in SCOPe 2.07: d4pjag1, d4pjag2
  • Chain 'H':
    Compound: TCR-beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PJA
    Domains in SCOPe 2.07: d4pjah1, d4pjah2
  • Heterogens: 2LJ, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4pjaA (A:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
awasieldpqssnlyschvehsgvhmvlqvp

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjaA (A:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
awasiellyschvehsgvhmvlqv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4pjaB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjaB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4pjaC (C:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
awasieldpqssnlyschvehsgvhmvlqvp

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjaC (C:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrkvtalfckahgfyppeiymtwmkngeeiidygdilpsgdgtyqawasiell
yschvehsgvhmvlqv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4pjaD (D:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjaD (D:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwd

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4pjaE (E:)
hmgqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekg
rfssflsrskgysylllkelqmkdsasylcagmdsnyqliwgagtkliikpdiqnpdpav
yqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnks
dfacanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjaE (E:)
qnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrfs
sflsrskgysylllkelqmkdsasylcagmdsnyqliwgagtkliikpdiqnpdpavyql
rdsvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnfacanafnnsi
ipedtffp

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4pjaF (F:)
hmnagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkg
evpngynvsrlnkrefslrlesaapsqtsvyfcastlgqegqpqhfgegsrltvledlkn
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjaF (F:)
gvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgevpn
gynvsrlnkrefslrlesaapsqtsvyfcastlgqegqpqhfgegsrltvledlknvfpp
evavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpal
ndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsae

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4pjaG (G:)
hmgqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekg
rfssflsrskgysylllkelqmkdsasylcagmdsnyqliwgagtkliikpdiqnpdpav
yqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnks
dfacanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjaG (G:)
gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
ssflsrskgysylllkelqmkdsasylcagmdsnyqliwgagtkliikpdiqnpdpavyq
lrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsndfac
anafnnsiipedtffp

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4pjaH (H:)
hmnagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkg
evpngynvsrlnkrefslrlesaapsqtsvyfcastlgqegqpqhfgegsrltvledlkn
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >4pjaH (H:)
gvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgevpn
gynvsrlnkrefslrlesaapsqtsvyfcastlgqegqpqhfgegsrltvledlknvfpp
evavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpal
ndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg