PDB entry 4pir

View 4pir on RCSB PDB site
Description: x-ray structure of the mouse serotonin 5-ht3 receptor
Deposited on 2014-05-09, released 2014-08-06
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 3.5 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 5-hydroxytryptamine receptor 3A
    Species: Mus musculus [TaxId:10090]
    Gene: Htr3a, 5ht3, Htr3
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: 5-hydroxytryptamine receptor 3A
    Species: Mus musculus [TaxId:10090]
    Gene: Htr3a, 5ht3, Htr3
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: 5-hydroxytryptamine receptor 3A
    Species: Mus musculus [TaxId:10090]
    Gene: Htr3a, 5ht3, Htr3
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: 5-hydroxytryptamine receptor 3A
    Species: Mus musculus [TaxId:10090]
    Gene: Htr3a, 5ht3, Htr3
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: 5-hydroxytryptamine receptor 3A
    Species: Mus musculus [TaxId:10090]
    Gene: Htr3a, 5ht3, Htr3
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: vhh15
    Species: Lama glama [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PIR (0-End)
  • Chain 'G':
    Compound: vhh15
    Species: Lama glama [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PIR (0-123)
  • Chain 'H':
    Compound: vhh15
    Species: Lama glama [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PIR (0-123)
  • Chain 'I':
    Compound: vhh15
    Species: Lama glama [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PIR (0-123)
  • Chain 'J':
    Compound: vhh15
    Species: Lama glama [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PIR (0-123)
  • Heterogens: CL, SO4, NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4pirA (A:)
atqardttqpallrlsdhllanykkgvrpvrdwrkpttvsidvimyailnvdeknqvltt
yiwyrqywtdeflqwtpedfdnvtklsiptdsiwvpdilinefvdvgkspnipyvyvhhr
gevqnykplqlvtacsldiynfpfdvqncsltftswlhtiqdinitlwrspeevrsdksi
finqgewellevfpqfkefsidisnsyaemkfyviirrrplfyavslllpsiflmvvdiv
gfclppdsgervsfkitlllgysvfliivsdtlpataigtpligvyfvvcmallvislae
tifivrlvhkqdlqrpvpdwlrhlvldriawilclgeqpmahrppatfqanktddcsamg
nhcshvggpqdlektprgrgsplpppreaslavrgllqelssirhflekrdemrevardw
lrvgyvldrllfriyllavlaysitlvtlwsiwhss

    Sequence, based on observed residues (ATOM records):
    >4pirA (A:)
tqpallrlsdhllanykkgvrpvrdwrkpttvsidvimyailnvdeknqvlttyiwyrqy
wtdeflqwtpedfdnvtklsiptdsiwvpdilinefvdvgkspnipyvyvhhrgevqnyk
plqlvtacsldiynfpfdvqncsltftswlhtiqdinitlwrspeevrsdksifinqgew
ellevfpqfkefsidisnsyaemkfyviirrrplfyavslllpsiflmvvdivgfclppd
sgervsfkitlllgysvfliivsdtlpatpligvyfvvcmallvislaetifivrlvhkq
dlqrpvpdwlrhlvldriawilcvrgllqelssirhflekrdemrevardwlrvgyvldr
llfriyllavlaysitlvtlwsi

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4pirB (B:)
atqardttqpallrlsdhllanykkgvrpvrdwrkpttvsidvimyailnvdeknqvltt
yiwyrqywtdeflqwtpedfdnvtklsiptdsiwvpdilinefvdvgkspnipyvyvhhr
gevqnykplqlvtacsldiynfpfdvqncsltftswlhtiqdinitlwrspeevrsdksi
finqgewellevfpqfkefsidisnsyaemkfyviirrrplfyavslllpsiflmvvdiv
gfclppdsgervsfkitlllgysvfliivsdtlpataigtpligvyfvvcmallvislae
tifivrlvhkqdlqrpvpdwlrhlvldriawilclgeqpmahrppatfqanktddcsamg
nhcshvggpqdlektprgrgsplpppreaslavrgllqelssirhflekrdemrevardw
lrvgyvldrllfriyllavlaysitlvtlwsiwhss

    Sequence, based on observed residues (ATOM records):
    >4pirB (B:)
tqpallrlsdhllanykkgvrpvrdwrkpttvsidvimyailnvdeknqvlttyiwyrqy
wtdeflqwtpedfdnvtklsiptdsiwvpdilinefvdvgkspnipyvyvhhrgevqnyk
plqlvtacsldiynfpfdvqncsltftswlhtiqdinitlwrspeevrsdksifinqgew
ellevfpqfkefsidisnsyaemkfyviirrrplfyavslllpsiflmvvdivgfclppd
sgervsfkitlllgysvfliivsdtlpatpligvyfvvcmallvislaetifivrlvhkq
dlqrpvpdwlrhlvldriawilcvrgllqelssirhflekrdemrevardwlrvgyvldr
llfriyllavlaysitlvtlwsi

  • Chain 'C':
    Sequence, based on SEQRES records:
    >4pirC (C:)
atqardttqpallrlsdhllanykkgvrpvrdwrkpttvsidvimyailnvdeknqvltt
yiwyrqywtdeflqwtpedfdnvtklsiptdsiwvpdilinefvdvgkspnipyvyvhhr
gevqnykplqlvtacsldiynfpfdvqncsltftswlhtiqdinitlwrspeevrsdksi
finqgewellevfpqfkefsidisnsyaemkfyviirrrplfyavslllpsiflmvvdiv
gfclppdsgervsfkitlllgysvfliivsdtlpataigtpligvyfvvcmallvislae
tifivrlvhkqdlqrpvpdwlrhlvldriawilclgeqpmahrppatfqanktddcsamg
nhcshvggpqdlektprgrgsplpppreaslavrgllqelssirhflekrdemrevardw
lrvgyvldrllfriyllavlaysitlvtlwsiwhss

    Sequence, based on observed residues (ATOM records):
    >4pirC (C:)
tqpallrlsdhllanykkgvrpvrdwrkpttvsidvimyailnvdeknqvlttyiwyrqy
wtdeflqwtpedfdnvtklsiptdsiwvpdilinefvdvgkspnipyvyvhhrgevqnyk
plqlvtacsldiynfpfdvqncsltftswlhtiqdinitlwrspeevrsdksifinqgew
ellevfpqfkefsidisnsyaemkfyviirrrplfyavslllpsiflmvvdivgfclppd
sgervsfkitlllgysvfliivsdtlpatpligvyfvvcmallvislaetifivrlvhkq
dlqrpvpdwlrhlvldriawilcvrgllqelssirhflekrdemrevardwlrvgyvldr
llfriyllavlaysitlvtlwsiw

  • Chain 'D':
    Sequence, based on SEQRES records:
    >4pirD (D:)
atqardttqpallrlsdhllanykkgvrpvrdwrkpttvsidvimyailnvdeknqvltt
yiwyrqywtdeflqwtpedfdnvtklsiptdsiwvpdilinefvdvgkspnipyvyvhhr
gevqnykplqlvtacsldiynfpfdvqncsltftswlhtiqdinitlwrspeevrsdksi
finqgewellevfpqfkefsidisnsyaemkfyviirrrplfyavslllpsiflmvvdiv
gfclppdsgervsfkitlllgysvfliivsdtlpataigtpligvyfvvcmallvislae
tifivrlvhkqdlqrpvpdwlrhlvldriawilclgeqpmahrppatfqanktddcsamg
nhcshvggpqdlektprgrgsplpppreaslavrgllqelssirhflekrdemrevardw
lrvgyvldrllfriyllavlaysitlvtlwsiwhss

    Sequence, based on observed residues (ATOM records):
    >4pirD (D:)
tqpallrlsdhllanykkgvrpvrdwrkpttvsidvimyailnvdeknqvlttyiwyrqy
wtdeflqwtpedfdnvtklsiptdsiwvpdilinefvdvgkspnipyvyvhhrgevqnyk
plqlvtacsldiynfpfdvqncsltftswlhtiqdinitlwrspeevrsdksifinqgew
ellevfpqfkefsidisnsyaemkfyviirrrplfyavslllpsiflmvvdivgfclppd
sgervsfkitlllgysvfliivsdtlpatpligvyfvvcmallvislaetifivrlvhkq
dlqrpvpdwlrhlvldriawilcvrgllqelssirhflekrdemrevardwlrvgyvldr
llfriyllavlaysitlvtlwsiw

  • Chain 'E':
    Sequence, based on SEQRES records:
    >4pirE (E:)
atqardttqpallrlsdhllanykkgvrpvrdwrkpttvsidvimyailnvdeknqvltt
yiwyrqywtdeflqwtpedfdnvtklsiptdsiwvpdilinefvdvgkspnipyvyvhhr
gevqnykplqlvtacsldiynfpfdvqncsltftswlhtiqdinitlwrspeevrsdksi
finqgewellevfpqfkefsidisnsyaemkfyviirrrplfyavslllpsiflmvvdiv
gfclppdsgervsfkitlllgysvfliivsdtlpataigtpligvyfvvcmallvislae
tifivrlvhkqdlqrpvpdwlrhlvldriawilclgeqpmahrppatfqanktddcsamg
nhcshvggpqdlektprgrgsplpppreaslavrgllqelssirhflekrdemrevardw
lrvgyvldrllfriyllavlaysitlvtlwsiwhss

    Sequence, based on observed residues (ATOM records):
    >4pirE (E:)
tqpallrlsdhllanykkgvrpvrdwrkpttvsidvimyailnvdeknqvlttyiwyrqy
wtdeflqwtpedfdnvtklsiptdsiwvpdilinefvdvgkspnipyvyvhhrgevqnyk
plqlvtacsldiynfpfdvqncsltftswlhtiqdinitlwrspeevrsdksifinqgew
ellevfpqfkefsidisnsyaemkfyviirrrplfyavslllpsiflmvvdivgfclppd
sgervsfkitlllgysvfliivsdtlpatpligvyfvvcmallvislaetifivrlvhkq
dlqrpvpdwlrhlvldriawilcvrgllqelssirhflekrdemrevardwlrvgyvldr
llfriyllavlaysitlvtlwsi

  • Chain 'F':
    Sequence, based on SEQRES records:
    >4pirF (F:)
dvqlvesggglvqpggslrlscaysgslfsilrmdwyrqapgkerelvagitrdaagyad
stnyadsvkgrftisrdsakntvylqmnslkpedtavyycnadartitgradywgqgtqv
tvss

    Sequence, based on observed residues (ATOM records):
    >4pirF (F:)
dvqlvesggglvqpggslrlscaysgslfsilrmdwyrqapgkerelvagitrdaagyad
stnyadsvkgrftisrdsakntvylqmnslkpedtavyycnadartitgradywgqgtqv
tv

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records:
    >4pirG (G:)
dvqlvesggglvqpggslrlscaysgslfsilrmdwyrqapgkerelvagitrdaagyad
stnyadsvkgrftisrdsakntvylqmnslkpedtavyycnadartitgradywgqgtqv
tvss

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records:
    >4pirH (H:)
dvqlvesggglvqpggslrlscaysgslfsilrmdwyrqapgkerelvagitrdaagyad
stnyadsvkgrftisrdsakntvylqmnslkpedtavyycnadartitgradywgqgtqv
tvss

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records:
    >4pirI (I:)
dvqlvesggglvqpggslrlscaysgslfsilrmdwyrqapgkerelvagitrdaagyad
stnyadsvkgrftisrdsakntvylqmnslkpedtavyycnadartitgradywgqgtqv
tvss

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records:
    >4pirJ (J:)
dvqlvesggglvqpggslrlscaysgslfsilrmdwyrqapgkerelvagitrdaagyad
stnyadsvkgrftisrdsakntvylqmnslkpedtavyycnadartitgradywgqgtqv
tvss