PDB entry 4pcf

View 4pcf on RCSB PDB site
Description: Structure-based protein engineering of a monomeric triosephosphate isomerase towards changing substrate specificity
Class: isomerase
Keywords: triosephosphate isomerase, tim barrel, protein engineering, substrate specificity, isomerase
Deposited on 2014-04-15, released 2015-04-22
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-04-22, with a file datestamp of 2015-04-17.
Experiment type: XRAY
Resolution: 2.71 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ma18-TIM
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PCF (Start-237)
    Domains in SCOPe 2.06: d4pcfa_
  • Chain 'B':
    Compound: Ma18-TIM
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PCF (Start-237)
    Domains in SCOPe 2.06: d4pcfb_
  • Chain 'C':
    Compound: Ma18-TIM
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Database cross-references and differences (RAF-indexed):
    • PDB 4PCF (Start-237)
    Domains in SCOPe 2.06: d4pcfc_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4pcfA (A:)
mskpqpiaaanwksgspdslsglidlfnstsinhdvqcvvastfvhlamtkerlshpkfv
iaaqnagntdalaslkdfgvnwivlghferrwyygetneivadkvaaavasgfmviacig
etlqeresgrtavvvltqiaaiakklkkadwakvviayepvwaigtgkvvtpqqaqeaha
lirswvsskigadvagelrilyggsvngknartlyqqrdvngflaglkpefvdiikatq

    Sequence, based on observed residues (ATOM records): (download) 
    >4pcfA (A:)
skpqpiaaanwksslsglidlfnstsinhdvqcvvastfvhlamtkerlshpkfviaaqn
agntdalaslkdfgvnwivlghferrwyygetneivadkvaaavasgfmviacigetlqe
resgrtavvvltqiaaiakklkkadwakvviayepvwaigtgkvvtpqqaqeahalirsw
vsskigadvagelrilyggsvngknartlyqqrdvngflaglkpefvdiikatq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4pcfB (B:)
mskpqpiaaanwksgspdslsglidlfnstsinhdvqcvvastfvhlamtkerlshpkfv
iaaqnagntdalaslkdfgvnwivlghferrwyygetneivadkvaaavasgfmviacig
etlqeresgrtavvvltqiaaiakklkkadwakvviayepvwaigtgkvvtpqqaqeaha
lirswvsskigadvagelrilyggsvngknartlyqqrdvngflaglkpefvdiikatq

    Sequence, based on observed residues (ATOM records): (download) 
    >4pcfB (B:)
skpqpiaaanwksspdslsglidlfnstsinhdvqcvvastfvhlamtkerlshpkfvia
aqnagntdalaslkdfgvnwivlghferrwyygetneivadkvaaavasgfmviaciget
lqeresgrtavvvltqiaaiakklkkadwakvviayepvwaigtgkvvtpqqaqeahali
rswvsskigadvagelrilyggsvngknartlyqqrdvngflaglkpefvdiikat

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4pcfC (C:)
mskpqpiaaanwksgspdslsglidlfnstsinhdvqcvvastfvhlamtkerlshpkfv
iaaqnagntdalaslkdfgvnwivlghferrwyygetneivadkvaaavasgfmviacig
etlqeresgrtavvvltqiaaiakklkkadwakvviayepvwaigtgkvvtpqqaqeaha
lirswvsskigadvagelrilyggsvngknartlyqqrdvngflaglkpefvdiikatq

    Sequence, based on observed residues (ATOM records): (download) 
    >4pcfC (C:)
skpqpiaaanwksgspdslsglidlfnstsinhdvqcvvastfvhlamtkerlshpkfvi
aaqnagntdalaslkdfgvnwivlghferrwyygetneivadkvaaavasgfmviacige
tlqeresgrtavvvltqiaaiakklkkadwakvviayepvwaigtgkvvtpqqaqeahal
irswvsskigadvagelrilyggsvngknartlyqqrdvngflaglkpefvdiikatq