PDB entry 4pbw

View 4pbw on RCSB PDB site
Description: Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with TrkC
Class: signaling protein
Keywords: Receptor protein tyrosine phosphatase (RPTP), Synapse Cell signalling Cell surface receptor, signaling protein
Deposited on 2014-04-14, released 2014-11-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 3.05 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NT-3 growth factor receptor
    Species: Gallus gallus [TaxId:9031]
    Gene: NTRK3, TRKC
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q91044 (3-273)
      • expression tag (1-2)
      • engineered mutation (43)
      • engineered mutation (134)
      • engineered mutation (203)
      • engineered mutation (230)
      • engineered mutation (238)
      • engineered mutation (265)
  • Chain 'B':
    Compound: NT-3 growth factor receptor
    Species: Gallus gallus [TaxId:9031]
    Gene: NTRK3, TRKC
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q91044 (3-273)
      • expression tag (2)
      • engineered mutation (43)
      • engineered mutation (134)
      • engineered mutation (203)
      • engineered mutation (230)
      • engineered mutation (238)
      • engineered mutation (265)
  • Chain 'C':
    Compound: NT-3 growth factor receptor
    Species: Gallus gallus [TaxId:9031]
    Gene: NTRK3, TRKC
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q91044 (3-273)
      • expression tag (2)
      • engineered mutation (134)
      • engineered mutation (203)
      • engineered mutation (230)
      • engineered mutation (238)
      • engineered mutation (265)
  • Chain 'D':
    Compound: protein-tyrosine phosphatase crypalpha1 isoform
    Species: Gallus gallus [TaxId:9031]
    Gene: CRYPalpha1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pbwd1, d4pbwd2
  • Chain 'E':
    Compound: protein-tyrosine phosphatase crypalpha1 isoform
    Species: Gallus gallus [TaxId:9031]
    Gene: CRYPalpha1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pbwe1, d4pbwe2
  • Chain 'F':
    Compound: protein-tyrosine phosphatase crypalpha1 isoform
    Species: Gallus gallus [TaxId:9031]
    Gene: CRYPalpha1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4pbwf1, d4pbwf2
  • Heterogens: NAG

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4pbwD (D:)
etgesppvfikkpvdqigvsggvasfvcqatgdpkprvtwnkkgkkvnsqrfetiefdes
agavlriqplrtprdeniyecvaqnphgevtvhakltvlredqlppgfpnidmgpqlkvv
ertrtatmlcaasgnpdpeitwfkdflpvdpstsngrikqlrsgglqiesseetdqgkye
cvasnsagvrysspanlyvrvrrvaprfsilpvsheimpggnvnitcvavgspmpyvkwm
qgaedltpeddmpvgrnvleltdvkdsanytcvamsslgvieavaqitvkskghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4pbwD (D:)
esppvfikkpvdqigvsggvasfvcqatgdpkprvtwnvnsqrfetiefdesagavlriq
plrtprdeniyecvaqnphgevtvhakltvlredqlppgfpnidmgpqlkvvertrtatm
lcaasgnpdpeitwfkdflpvdpstsngrikqlrsgglqiesseetdqgkyecvasnsag
vrysspanlyvrv

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4pbwE (E:)
etgesppvfikkpvdqigvsggvasfvcqatgdpkprvtwnkkgkkvnsqrfetiefdes
agavlriqplrtprdeniyecvaqnphgevtvhakltvlredqlppgfpnidmgpqlkvv
ertrtatmlcaasgnpdpeitwfkdflpvdpstsngrikqlrsgglqiesseetdqgkye
cvasnsagvrysspanlyvrvrrvaprfsilpvsheimpggnvnitcvavgspmpyvkwm
qgaedltpeddmpvgrnvleltdvkdsanytcvamsslgvieavaqitvkskghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4pbwE (E:)
esppvfikkpvdqigvsggvasfvcqatgdpkprvtwnvnsqrfetiefdesagavlriq
plrtprdeniyecvaqnphgevtvhakltvlredqlppgfpnidmgpqlkvvertrtatm
lcaasgnpdpeitwfkdflpvdpstsngrikqlrsgglqiesseetdqgkyecvasnsag
vrysspanlyvrvr

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4pbwF (F:)
etgesppvfikkpvdqigvsggvasfvcqatgdpkprvtwnkkgkkvnsqrfetiefdes
agavlriqplrtprdeniyecvaqnphgevtvhakltvlredqlppgfpnidmgpqlkvv
ertrtatmlcaasgnpdpeitwfkdflpvdpstsngrikqlrsgglqiesseetdqgkye
cvasnsagvrysspanlyvrvrrvaprfsilpvsheimpggnvnitcvavgspmpyvkwm
qgaedltpeddmpvgrnvleltdvkdsanytcvamsslgvieavaqitvkskghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4pbwF (F:)
esppvfikkpvdqigvsggvasfvcqatgdpkprvtwnvnsqrfetiefdesagavlriq
plrtprdeniyecvaqnphgevtvhakltvlredqlppgfpnidmgpqlkvvertrtatm
lcaasgnpdpeitwfkdflpvdpstsngrikqlrsgglqiesseetdqgkyecvasnsag
vrysspanlyvr