PDB entry 4p8y

View 4p8y on RCSB PDB site
Description: crystal structure of m. tuberculosis dpre1 in complex with the non- covalent inhibitor ty21c
Deposited on 2014-04-01, released 2014-12-10
The last revision was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Probable decaprenylphosphoryl-beta-D-ribose oxidase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: dprE1, Rv3790, MT3898
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Probable decaprenylphosphoryl-beta-D-ribose oxidase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: dprE1, Rv3790, MT3898
    Database cross-references and differences (RAF-indexed):
  • Heterogens: FAD, 38C, IMD, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4p8yA (A:)
gsshhhhhhssglvprgshmlsvgatttatrltgwgrtapsvanvlrtpdaemivkavar
vaesgggrgaiarglgrsygdnaqnggglvidmtplntihsidadtklvdidagvnldql
mkaalpfglwvpvlpgtrqvtvggaiacdihgknhhsagsfgnhvrsmdlltadgeirhl
tptgedaelfwatvggngltgiimratiemtptstayfiadgdvtasldetialhsdgse
arytyssawfdaisappklgraavsrgrlatveqlpaklrseplkfdapqlltlpdvfpn
glankytfgpigelwyrksgtyrgkvqnltqfyhpldmfgewnraygpagflqyqfvipt
eavdefkkiigviqasghysflnvfklfgprnqaplsfpipgwnicvdfpikdglgkfvs
eldrrvlefggrlytakdsrttaetfhamyprvdewisvrrkvdplrvfasdmarrlell

    Sequence, based on observed residues (ATOM records):
    >4p8yA (A:)
vgatttatrltgwgrtapsvanvlrtpdaemivkavarvaesgggrgaiarglgrsygdn
aqnggglvidmtplntihsidadtklvdidagvnldqlmkaalpfglwvpvlpgtrqvtv
ggaiacdihgknhhsagsfgnhvrsmdlltadgeirhltptgedaelfwatvggngltgi
imratiemtptstayfiadgdvtasldetialhsdgsearytyssawfdaisappklgra
avsrgrlatveqlpaklrseplkfdapqlltlpdvfpnglankytfgpigelwyrksgty
rgkvqnltqfyhpldmfgewnraagflqyqfvipteavdefkkiigviqasghysflnvf
klfgprnqaplsfpipgwnicvdfpikdglgkfvseldrrvlefggrlytakdsrttaet
fhamyprvdewisvrrkvdplrvfasdmarrlell

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4p8yB (B:)
gsshhhhhhssglvprgshmlsvgatttatrltgwgrtapsvanvlrtpdaemivkavar
vaesgggrgaiarglgrsygdnaqnggglvidmtplntihsidadtklvdidagvnldql
mkaalpfglwvpvlpgtrqvtvggaiacdihgknhhsagsfgnhvrsmdlltadgeirhl
tptgedaelfwatvggngltgiimratiemtptstayfiadgdvtasldetialhsdgse
arytyssawfdaisappklgraavsrgrlatveqlpaklrseplkfdapqlltlpdvfpn
glankytfgpigelwyrksgtyrgkvqnltqfyhpldmfgewnraygpagflqyqfvipt
eavdefkkiigviqasghysflnvfklfgprnqaplsfpipgwnicvdfpikdglgkfvs
eldrrvlefggrlytakdsrttaetfhamyprvdewisvrrkvdplrvfasdmarrlell

    Sequence, based on observed residues (ATOM records):
    >4p8yB (B:)
tttatrltgwgrtapsvanvlrtpdaemivkavarvaesgggrgaiarglgrsygdnaqn
ggglvidmtplntihsidadtklvdidagvnldqlmkaalpfglwvpvlpgtrqvtvgga
iacdihgknhhsagsfgnhvrsmdlltadgeirhltptgedaelfwatvggngltgiimr
atiemtptstayfiadgdvtasldetialhsdgsearytyssawfdaisappklgraavs
rgrlatveqlpaklrseplkfdapelwyrksgtyrgkvqnltqfygflqyqfvipteavd
efkkiigviqasghysflnvfklfgprnqaplsfpipgwnicvdfpikdglgkfvseldr
rvlefggrlytakdsrttaetfhamyprvdewisvrrkvdplrvfasdmarrlell