PDB entry 4p69

View 4p69 on RCSB PDB site
Description: acek (d477a) icdh complex
Deposited on 2014-03-22, released 2014-10-08
The last revision was dated 2018-05-30, with a file datestamp of 2018-05-25.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Isocitrate dehydrogenase kinase/phosphatase
    Species: Escherichia coli O157:H7 [TaxId:83334]
    Gene: aceK, Z5602, ECs4934
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8X607 (0-567)
      • engineered mutation (473)
  • Chain 'B':
    Compound: Isocitrate dehydrogenase kinase/phosphatase
    Species: Escherichia coli O157:H7 [TaxId:83334]
    Gene: aceK, Z5602, ECs4934
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8X607 (Start-567)
      • engineered mutation (473)
  • Chain 'C':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Escherichia coli [TaxId:83333]
    Gene: icd, icdA, icdE, b1136, JW1122
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Escherichia coli [TaxId:83333]
    Gene: icd, icdA, icdE, b1136, JW1122
    Database cross-references and differences (RAF-indexed):
  • Heterogens: AMP, ADP, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4p69A (A:)
glelliaqtilqgfdaqygrflevtsgaqqrfeqadwhavqqamknrihlydhhvglvve
qlrcitngqstdaefllrvkehytrllpdyprfeiaesffnsvycrlfdhrsltperlfi
fssqperrfrtiprplakdfhpdhgwesllmrvisdlplrlhwqnksrdihyiirhltet
lgpenlskshlqvanelfyrnkaawlvgklitpsgtlpfllpihqtddgelfidtclttt
aeasivfgfarsyfmvyaplpaalvewlreilpgkttaelymaigcqkhaktesyreylv
ylqgcneqfieapgirgmvmlvftlpgfdrvfkvikdkfapqkemsaahvracyqlvkeh
drvgrmadtqefenfvlekrhispalmelllqeaaekitdlgeqivirhlyierrmvpln
iwleqvegqqlrdaieeygnairqlaaanifpgdmlfknfgvtrhgrvvfydyaeicymt
evnfrdippprypedelasepwysvspgdvfpeefrhwlcadprigplfeemhadlfrad
ywralqnrireghvedvyayrrrqrfsv

    Sequence, based on observed residues (ATOM records):
    >4p69A (A:)
glelliaqtilqgfdaqygrflevtsgaqqrfeqadwhavqqamknrihlydhhvglvve
qlrcitnefllrvkehytrllpdyprfeiaesffnsvycrlfdhrsltperlfifssqpr
plakdfhpdhgwesllmrvisdlplrlhwqnksrdihyiirhltetlgpenlskshlqva
nelfyrnkaawlvgklitpsgtlpfllpihqtddgelfidtcltttaeasivfgfarsyf
mvyaplpaalvewlreilpgkttaelymaigcqkhaktesyreylvylqgcneqfieapg
irgmvmlvftlpgfdrvfkvikdkfapqkemsaahvracyqlvkehdrvgrmadtqefen
fvlekrhispalmelllqeaaekitdlgeqivirhlyierrmvplniwleqvegqqlrda
ieeygnairqlaaanifpgdmlfknfgvtrhgrvvfydyaeicymtevnfrdippprype
delasepwysvspgdvfpeefrhwlcadprigplfeemhadlfradywralqnrireghv
edvyayrrrqrfsv

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4p69B (B:)
glelliaqtilqgfdaqygrflevtsgaqqrfeqadwhavqqamknrihlydhhvglvve
qlrcitngqstdaefllrvkehytrllpdyprfeiaesffnsvycrlfdhrsltperlfi
fssqperrfrtiprplakdfhpdhgwesllmrvisdlplrlhwqnksrdihyiirhltet
lgpenlskshlqvanelfyrnkaawlvgklitpsgtlpfllpihqtddgelfidtclttt
aeasivfgfarsyfmvyaplpaalvewlreilpgkttaelymaigcqkhaktesyreylv
ylqgcneqfieapgirgmvmlvftlpgfdrvfkvikdkfapqkemsaahvracyqlvkeh
drvgrmadtqefenfvlekrhispalmelllqeaaekitdlgeqivirhlyierrmvpln
iwleqvegqqlrdaieeygnairqlaaanifpgdmlfknfgvtrhgrvvfydyaeicymt
evnfrdippprypedelasepwysvspgdvfpeefrhwlcadprigplfeemhadlfrad
ywralqnrireghvedvyayrrrqrfsv

    Sequence, based on observed residues (ATOM records):
    >4p69B (B:)
lelliaqtilqgfdaqygrflevtsgaqqrfeqadwhavqqamknrihlydhhvglvveq
lrcitnefllrvkehytrllpdyprfeiaesffnsvycrlfdhrsltperlfifssqper
rfrtiprplakdfhpdhgwesllmrvisdlplrlhwqnksrdihyiirhltetlgpenls
kshlqvanelfyrnkaawlvgklitpsgtlpfllpihqtddgelfidtcltttaeasivf
gfarsyfmvyaplpaalvewlreilpgkttaelymaigcqkhaktesyreylvylqgcne
qfieapgirgmvmlvftlpgfdrvfkvikdkfapqkemsaahvracyqlvkehdrvgrma
dtqefenfvlekrhispalmelllqeaaekitdlgeqivirhlyierrmvplniwleqve
gqqlrdaieeygnairqlaaanifpgdmlfknfgvtrhgrvvfydyaeicymtevnfrdi
ppprypedelasepwysvspgdvfpeefrhwlcadprigplfeemhadlfradywralqn
rireghvedvyayrrrqrfsv

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >4p69C (C:)
eskvvvpaqgkkitlqngklnvpenpiipyiegdgigvdvtpamlkvvdaavekaykger
kiswmeiytgekstqvygqdvwlpaetldlireyrvaikgplttpvgggirslnvalrqe
ldlyiclrpvryyqgtpspvkhpeltdmvifrensediyagiewkadsadaekvikflre
emgvkkirfpehcgigikpcseegtkrlvraaieyaiandrdsvtlvhkgnimkftegaf
kdwgyqlareefggelidggpwlkvknpntgkeivikdviadaflqqillrpaeydviac
mnlngdyisdalaaqvggigiapganigdecalfeathgtapkyagqdkvnpgsiilsae
mmlrhmgwteaadlivkgmegainaktvtydferlmdgakllkcsefgdaiienm

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >4p69D (D:)
eskvvvpaqgkkitlqngklnvpenpiipyiegdgigvdvtpamlkvvdaavekaykger
kiswmeiytgekstqvygqdvwlpaetldlireyrvaikgplttpvgggirslnvalrqe
ldlyiclrpvryyqgtpspvkhpeltdmvifrensediyagiewkadsadaekvikflre
emgvkkirfpehcgigikpcseegtkrlvraaieyaiandrdsvtlvhkgnimkftegaf
kdwgyqlareefggelidggpwlkvknpntgkeivikdviadaflqqillrpaeydviac
mnlngdyisdalaaqvggigiapganigdecalfeathgtapkyagqdkvnpgsiilsae
mmlrhmgwteaadlivkgmegainaktvtydferlmdgakllkcsefgdaiienm