PDB entry 4p66
View 4p66 on RCSB PDB site
Description: Electrostatics of Active Site Microenvironments of E. coli DHFR
Class: oxidoreductase
Keywords: OXIDOREDUCTASE, catalysis, electrostatics, catalytic cycle
Deposited on
2014-03-21, released
2014-07-16
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-12-25, with a file datestamp of
2019-12-20.
Experiment type: XRAY
Resolution: 1.84 Å
R-factor: N/A
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: dihydrofolate reductase
Species: Escherichia coli [TaxId:562]
Gene: folA, ECs0051, LF82_0721
Database cross-references and differences (RAF-indexed):
- Uniprot C3TR70 (0-158)
- engineered mutation (45)
- engineered mutation (84)
- engineered mutation (151)
Domains in SCOPe 2.08: d4p66a_ - Heterogens: MTX, NAP, CA, HOH