PDB entry 4p5a

View 4p5a on RCSB PDB site
Description: Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br UMP
Class: transferase
Keywords: Tetramer, UMP/dUMP methylase, ThyX homolog, TRANSFERASE
Deposited on 2014-03-15, released 2015-12-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-12-09, with a file datestamp of 2015-12-04.
Experiment type: XRAY
Resolution: 1.76 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase thyX
    Species: Streptomyces cacaoi subsp. asoensis [TaxId:249586]
    Gene: polB, thyX
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4p5aa_
  • Chain 'B':
    Compound: Thymidylate synthase thyX
    Species: Streptomyces cacaoi subsp. asoensis [TaxId:249586]
    Gene: polB, thyX
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4p5ab_
  • Chain 'C':
    Compound: Thymidylate synthase thyX
    Species: Streptomyces cacaoi subsp. asoensis [TaxId:249586]
    Gene: polB, thyX
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4p5ac_
  • Chain 'D':
    Compound: Thymidylate synthase thyX
    Species: Streptomyces cacaoi subsp. asoensis [TaxId:249586]
    Gene: polB, thyX
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4p5ad_
  • Heterogens: FAD, 5BU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4p5aA (A:)
mesprielrsditvelvdssasdlavvkaarvstagedandelydggstrglirylmrsr
hgspfehnsmtflvrapiftvrhlmrhrtwsfneesaryrevgaafyvpdatrllrqegk
pgdyryvggstddhqqvvrsatrayevafeeyqrlldsgiareiarlvlpvstysvlyat
cnaralmhflslrthrpdaayvshpqreiemvaeqmetawaklmpvtheaftafgrvsp

    Sequence, based on observed residues (ATOM records): (download) 
    >4p5aA (A:)
prielrsditvelvdssasdlavvkaarvstaggstrglirylmrsrhgspfehnsmtfl
vrapiftvrhlmrhrtwsfneesaryrevgaafyvpdatrllrqegkpgdyryvggstdd
hqqvvrsatrayevafeeyqrlldsgiareiarlvlpvstysvlyatcnaralmhflslr
thrpdaayvshpqreiemvaeqmetawaklmpvtheaftafgrvsp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4p5aB (B:)
mesprielrsditvelvdssasdlavvkaarvstagedandelydggstrglirylmrsr
hgspfehnsmtflvrapiftvrhlmrhrtwsfneesaryrevgaafyvpdatrllrqegk
pgdyryvggstddhqqvvrsatrayevafeeyqrlldsgiareiarlvlpvstysvlyat
cnaralmhflslrthrpdaayvshpqreiemvaeqmetawaklmpvtheaftafgrvsp

    Sequence, based on observed residues (ATOM records): (download) 
    >4p5aB (B:)
prielrsditvelvdssasdlavvkaarvstydggstrglirylmrsrhgspfehnsmtf
lvrapiftvrhlmrhrtwsfneesaryrevgaafyvpdatrllrqegkpgdyryvggstd
dhqqvvrsatrayevafeeyqrlldsgiareiarlvlpvstysvlyatcnaralmhflsl
rthrpdaayvshpqreiemvaeqmetawaklmpvtheaftafgrvsp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4p5aC (C:)
mesprielrsditvelvdssasdlavvkaarvstagedandelydggstrglirylmrsr
hgspfehnsmtflvrapiftvrhlmrhrtwsfneesaryrevgaafyvpdatrllrqegk
pgdyryvggstddhqqvvrsatrayevafeeyqrlldsgiareiarlvlpvstysvlyat
cnaralmhflslrthrpdaayvshpqreiemvaeqmetawaklmpvtheaftafgrvsp

    Sequence, based on observed residues (ATOM records): (download) 
    >4p5aC (C:)
prielrsditvelvdssasdlavvkaarvststrglirylmrsrhgspfehnsmtflvra
piftvrhlmrhrtwsfneesaryrevgaafyvpdatrllrqegkpgdyryvggstddhqq
vvrsatrayevafeeyqrlldsgiareiarlvlpvstysvlyatcnaralmhflslrthr
pdaayvshpqreiemvaeqmetawaklmpvtheaftafgrvsp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4p5aD (D:)
mesprielrsditvelvdssasdlavvkaarvstagedandelydggstrglirylmrsr
hgspfehnsmtflvrapiftvrhlmrhrtwsfneesaryrevgaafyvpdatrllrqegk
pgdyryvggstddhqqvvrsatrayevafeeyqrlldsgiareiarlvlpvstysvlyat
cnaralmhflslrthrpdaayvshpqreiemvaeqmetawaklmpvtheaftafgrvsp

    Sequence, based on observed residues (ATOM records): (download) 
    >4p5aD (D:)
rielrsditvelvdssasdlavvkaarvstdggstrglirylmrsrhgspfehnsmtflv
rapiftvrhlmrhrtwsfneesaryrevgaafyvpdatrllrqegkpgdyryvggstddh
qqvvrsatrayevafeeyqrlldsgiareiarlvlpvstysvlyatcnaralmhflslrt
hrpdaayvshpqreiemvaeqmetawaklmpvtheaftafgrvsp