PDB entry 4p4c

View 4p4c on RCSB PDB site
Description: Human EphA3 Kinase domain in complex with quinoxaline derivatives
Class: transferase/transferase inhibitor
Keywords: transferase-transferase inhibitor complex
Deposited on 2014-03-12, released 2014-08-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: EPH receptor A3
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHA3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4p4ca_
  • Heterogens: 25Q, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4p4cA (A:)
mgsshhhhhhssglvprgstqtvhefakeldatnisidkvvgagefgevcsgrlklpskk
eisvaiktlkvgytekqrrdflgeasimgqfdhpniirlegvvtkskpvmivteymengs
ldsflrkhdaqftviqlvgmlrgiasgmkylsdmgyvhrdlaarnilinsnlvckvsdfg
lsrvleddpeaayttrggkipirwtspeaiayrkftsasdvwsygivlwevmsygerpyw
emsnqdvikavdegyrlpppmdcpaalyqlmldcwqkdrnnrpkfeqivsildklirnpg
slkiitsaaarpsnllldqsnvdittfrttgdwlngvwtahckeiftgveysscdtiaki
s

    Sequence, based on observed residues (ATOM records): (download) 
    >4p4cA (A:)
akeldatnisidkvvgagefgevcsgrlklpskkeisvaiktlkvgytekqrrdflgeas
imgqfdhpniirlegvvtkskpvmivteymengsldsflrkhdaqftviqlvgmlrgias
gmkylsdmgyvhrdlaarnilinsnlvckvsdfpirwtspeaiayrkftsasdvwsygiv
lwevmsygerpywemsnqdvikavdegyrlpppmdcpaalyqlmldcwqkdrnnrpkfeq
ivsildklirnpgslkiitpsnllld