PDB entry 4otl

View 4otl on RCSB PDB site
Description: X-ray Crystal Structure of Serine Hydroxymethyl Transferase from Burkholderia cenocepacia bound to PLP and Glycine
Class: transferase
Keywords: Structural Genomics, NIAID, National Institute of Allergy and Infectious Diseases, Seattle Structural Genomics Center for Infectious Disease, SSGCID, serine hydroxymethyl transferase, transferase
Deposited on 2014-02-13, released 2014-04-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-04-23, with a file datestamp of 2014-04-18.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.182
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine hydroxymethyltransferase
    Species: BURKHOLDERIA CENOCEPACIA [TaxId:216591]
    Gene: glyA, BCAL3197
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4otla_
  • Chain 'B':
    Compound: serine hydroxymethyltransferase
    Species: BURKHOLDERIA CENOCEPACIA [TaxId:216591]
    Gene: glyA, BCAL3197
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4otlb_
  • Chain 'C':
    Compound: serine hydroxymethyltransferase
    Species: BURKHOLDERIA CENOCEPACIA [TaxId:216591]
    Gene: glyA, BCAL3197
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4otlc_
  • Chain 'D':
    Compound: serine hydroxymethyltransferase
    Species: BURKHOLDERIA CENOCEPACIA [TaxId:216591]
    Gene: glyA, BCAL3197
    Database cross-references and differences (RAF-indexed):
    • Uniprot B4ECY9 (8-422)
      • expression tag (7)
    Domains in SCOPe 2.08: d4otld1, d4otld2
  • Heterogens: PLP, GLY, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4otlA (A:)
mahhhhhhmfdraqstianvdpeifaaieqenrrqedhieliasenytspavmaaqgsql
tnkyaegypgkryyggceyvdvveqlaidrvkqlfgaeaanvqpnsgsqanqgvffamlk
pgdtimgmslahgghlthgspvnmsgkwfnvvsyglnenedidydaaeklanehkpkliv
agasafalkidferlakiaksvgaylmvdmahyagliaagvypnpvphadfvtttthksl
rgprggvilmkaeyekpinsaifpgiqggplmhviaakavafkealspefkeyqqkvven
arvlaetlvkrglrivsgrteshvmlvdlrakhitgkaaeaalgaahitvnknaipndpe
kpfvtsgirlgspamttrgfgpaeaeqvgnliadvlenpedaatiervraqvaeltkrfp
vyr

    Sequence, based on observed residues (ATOM records): (download) 
    >4otlA (A:)
stianvdpeifaaieqenrrqedhieliasenytspavmaaqgsqltnkyaegypgkryy
ggceyvdvveqlaidrvkqlfgaeaanvqpnsgsqanqgvffamlkpgdtimgmslahgg
hlthgspvnmsgkwfnvvsyglnenedidydaaeklanehkpklivagasafalkidfer
lakiaksvgaylmvdmahyagliaagvypnpvphadfvtttthkslrgprggvilmkaey
ekpinsaifpgiqggplmhviaakavafkealspefkeyqqkvvenarvlaetlvkrglr
ivsgrteshvmlvdlrakhitgkaaeaalgaahitvnknaipndpekpfvtsgirlgspa
mttrgfgpaeaeqvgnliadvlenpedaatiervraqvaeltkrfpvyr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4otlB (B:)
mahhhhhhmfdraqstianvdpeifaaieqenrrqedhieliasenytspavmaaqgsql
tnkyaegypgkryyggceyvdvveqlaidrvkqlfgaeaanvqpnsgsqanqgvffamlk
pgdtimgmslahgghlthgspvnmsgkwfnvvsyglnenedidydaaeklanehkpkliv
agasafalkidferlakiaksvgaylmvdmahyagliaagvypnpvphadfvtttthksl
rgprggvilmkaeyekpinsaifpgiqggplmhviaakavafkealspefkeyqqkvven
arvlaetlvkrglrivsgrteshvmlvdlrakhitgkaaeaalgaahitvnknaipndpe
kpfvtsgirlgspamttrgfgpaeaeqvgnliadvlenpedaatiervraqvaeltkrfp
vyr

    Sequence, based on observed residues (ATOM records): (download) 
    >4otlB (B:)
stianvdpeifaaieqenrrqedhieliasenytspavmaaqgsqltnkyaegypgkryy
ggceyvdvveqlaidrvkqlfgaeaanvqpnsgsqanqgvffamlkpgdtimgmslahgg
hlthgspvnmsgkwfnvvsyglnenedidydaaeklanehkpklivagasafalkidfer
lakiaksvgaylmvdmahyagliaagvypnpvphadfvtttthkslrgprggvilmkaey
ekpinsaifpgiqggplmhviaakavafkealspefkeyqqkvvenarvlaetlvkrglr
ivsgrteshvmlvdlrakhitgkaaeaalgaahitvnknaipndpekpfvtsgirlgspa
mttrgfgpaeaeqvgnliadvlenpedaatiervraqvaeltkrfpvyr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4otlC (C:)
mahhhhhhmfdraqstianvdpeifaaieqenrrqedhieliasenytspavmaaqgsql
tnkyaegypgkryyggceyvdvveqlaidrvkqlfgaeaanvqpnsgsqanqgvffamlk
pgdtimgmslahgghlthgspvnmsgkwfnvvsyglnenedidydaaeklanehkpkliv
agasafalkidferlakiaksvgaylmvdmahyagliaagvypnpvphadfvtttthksl
rgprggvilmkaeyekpinsaifpgiqggplmhviaakavafkealspefkeyqqkvven
arvlaetlvkrglrivsgrteshvmlvdlrakhitgkaaeaalgaahitvnknaipndpe
kpfvtsgirlgspamttrgfgpaeaeqvgnliadvlenpedaatiervraqvaeltkrfp
vyr

    Sequence, based on observed residues (ATOM records): (download) 
    >4otlC (C:)
fdraqstianvdpeifaaieqenrrqedhieliasenytspavmaaqgsqltnkyaegyp
gkryyggceyvdvveqlaidrvkqlfgaeaanvqpnsgsqanqgvffamlkpgdtimgms
lahgghlthgspvnmsgkwfnvvsyglnenedidydaaeklanehkpklivagasafalk
idferlakiaksvgaylmvdmahyagliaagvypnpvphadfvtttthkslrgprggvil
mkaeyekpinsaifpgiqggplmhviaakavafkealspefkeyqqkvvenarvlaetlv
krglrivsgrteshvmlvdlrakhitgkaaeaalgaahitvnknaipndpekpfvtsgir
lgspamttrgfgpaeaeqvgnliadvlenpedaatiervraqvaeltkrfpvyr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4otlD (D:)
mahhhhhhmfdraqstianvdpeifaaieqenrrqedhieliasenytspavmaaqgsql
tnkyaegypgkryyggceyvdvveqlaidrvkqlfgaeaanvqpnsgsqanqgvffamlk
pgdtimgmslahgghlthgspvnmsgkwfnvvsyglnenedidydaaeklanehkpkliv
agasafalkidferlakiaksvgaylmvdmahyagliaagvypnpvphadfvtttthksl
rgprggvilmkaeyekpinsaifpgiqggplmhviaakavafkealspefkeyqqkvven
arvlaetlvkrglrivsgrteshvmlvdlrakhitgkaaeaalgaahitvnknaipndpe
kpfvtsgirlgspamttrgfgpaeaeqvgnliadvlenpedaatiervraqvaeltkrfp
vyr

    Sequence, based on observed residues (ATOM records): (download) 
    >4otlD (D:)
hmfdraqstianvdpeifaaieqenrrqedhieliasenytspavmaaqgsqltnkyaeg
ypgkryyggceyvdvveqlaidrvkqlfgaeaanvqpnsgsqanqgvffamlkpgdtimg
mslahgghlthgspvnmsgkwfnvvsyglnenedidydaaeklanehkpklivagasafa
lkidferlakiaksvgaylmvdmahyagliaagvypnpvphadfvtttthkslrgprggv
ilmkaeyekpinsaifpgiqggplmhviaakavafkealspefkeyqqkvvenarvlaet
lvkrglrivsgrteshvmlvdlrakhitgkaaeaalgaahitvnknaipndpekpfvtsg
irlgspamttrgfgpaeaeqvgnliadvlenpedaatiervraqvaeltkrfpvyr