PDB entry 4otk

View 4otk on RCSB PDB site
Description: A structural characterization of the isoniazid Mycobacterium tuberculosis drug target, Rv2971, in its unliganded form
Class: oxidoreductase
Keywords: TIM Barrel, oxidoreductase
Deposited on 2014-02-13, released 2014-05-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mycobacterial Enzyme Rv2971
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: Rv2971, MT3049
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4otka_
  • Heterogens: MLI, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4otkA (A:)
mgsshhhhhhssglvprgshmasmtggqqmgrgsefvtgesgaaaapsitlndehtmpvl
glgvaelsddeteravsaaleigcrlidtayaygneaavgraiaasgvareelfvttkla
tpdqgftrsqeacrasldrlgldyvdlylihwpappvgkyvdawggmiqsrgegharsig
vsnftaenienlidltfvtpavnqielhpllnqdelrkanaqhtvvtqsycplalgrlld
nptvtsiaseyvktpaqvllrwnlqlgnavvvrsarperiasnfdvfdfelaaehmdalg
glndgtrvredpltyagt

    Sequence, based on observed residues (ATOM records): (download) 
    >4otkA (A:)
aaaapsitlndehtmpvlglgvaelsddeteravsaaleigcrlidtayaygneaavgra
iaasgvareelfvttklatpdqgftrsqeacrasldrlgldyvdlylihwpappvgkyvd
awggmiqsrgegharsigvsnftaenienlidltfvtpavnqielhpllnqdelrkanaq
htvvtqsycplalgrlldnptvtsiaseyvktpaqvllrwnlqlgnavvvrsarperias
nfdvfdfelaaehmdalgglndgtrvredpltyagt