PDB entry 4os3
View 4os3 on RCSB PDB site
Description: Three-dimensional structure of the C65A-W112F double mutant of Human lipocalin-type Prostaglandin D Synthase apo-form
Class: isomerase
Keywords: lipocalin-type prostaglandin-d synthase, isomerase
Deposited on
2014-02-12, released
2014-08-06
The last revision prior to the SCOPe 2.08 freeze date was dated
2014-12-17, with a file datestamp of
2014-12-12.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.222
AEROSPACI score: 0.55
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Prostaglandin-H2 D-isomerase
Species: Homo sapiens [TaxId:9606]
Gene: PTGDS, PDS
Database cross-references and differences (RAF-indexed):
- Uniprot P41222
- engineered mutation (64)
- engineered mutation (111)
Domains in SCOPe 2.08: d4os3a_ - Chain 'B':
Compound: Prostaglandin-H2 D-isomerase
Species: Homo sapiens [TaxId:9606]
Gene: PTGDS, PDS
Database cross-references and differences (RAF-indexed):
- Uniprot P41222
- engineered mutation (64)
- engineered mutation (111)
Domains in SCOPe 2.08: d4os3b_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4os3A (A:)
mathhtlwmglallgvlgdlqaapeaqvsvqpnfqqdkflgrwfsaglasnsswlrekka
alsmaksvvapatdgglnltstflrknqcetrtmllqpagslgsysyrsphfgstysvsv
vetdydqyallysqgskgpgedfrmatlysrtqtpraelkekftafckaqgftedtivfl
pqtdkcmteq
Sequence, based on observed residues (ATOM records): (download)
>4os3A (A:)
qvsvqpnfqqdkflgrwfsaglasnsswlrekkaalsmaksvvapatdgglnltstflrk
nqcetrtmllqpagslgsysyrsphfgstysvsvvetdydqyallysqgskgpgedfrma
tlysrtqtpraelkekftafckaqgftedtivflpqtdkcmte
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4os3B (B:)
mathhtlwmglallgvlgdlqaapeaqvsvqpnfqqdkflgrwfsaglasnsswlrekka
alsmaksvvapatdgglnltstflrknqcetrtmllqpagslgsysyrsphfgstysvsv
vetdydqyallysqgskgpgedfrmatlysrtqtpraelkekftafckaqgftedtivfl
pqtdkcmteq
Sequence, based on observed residues (ATOM records): (download)
>4os3B (B:)
vsvqpnfqqdkflgrwfsaglasnsswlrekkaalsmaksvvapatdgglnltstflrkn
qcetrtmllqpagslgsysyrsphfgstysvsvvetdydqyallysqgskgpgedfrmat
lysrtqtpraelkekftafckaqgftedtivflpqtdkcmte